Evidence map›Paper›PMID 42299068›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Defining Rational Photoelectron Routing for Targeted Intracellular Energy Transfer.

Hao Wang, Jialu Li, Yuhua Feng, Lin Wang, Donghao He, Cuiping Zeng, Zhonghua Cai, Kemeng Xiao, Bo Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao WangTechnology Innovation Center For Marine Ecology and Human Factor Assessment of Natural Resources Ministry, Tsinghua Shenzhen International Graduate School, Shenzhen, Guangdong Province, P. R. China.
Jialu LiState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.
Yuhua FengTechnology Innovation Center For Marine Ecology and Human Factor Assessment of Natural Resources Ministry, Tsinghua Shenzhen International Graduate School, Shenzhen, Guangdong Province, P. R. China.
Lin WangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.
Donghao HeState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.
Cuiping ZengState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.
Zhonghua CaiTechnology Innovation Center For Marine Ecology and Human Factor Assessment of Natural Resources Ministry, Tsinghua Shenzhen International Graduate School, Shenzhen, Guangdong Province, P. R. China.
Kemeng XiaoState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.
Bo WangState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Key Laboratory of Materials Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, P. R. China.ORCID 0000-0002-3022-1790

Funding

Guangdong Basic and Applied Basic Research Foundation 2022B1111080005Guangdong Basic and Applied Basic Research Foundation 2023A1515030212National Key R&D Program of China 2022YFA0912800Natural Science Foundation of China 22406192Natural Science Foundation of China 22508406Shenzhen Science and Technology Program RCYX20231211090115013Shenzhen Science and Technology Program ZDSYS20220606100606013
6 · The paper itself

Abstract

Microbial artificial photosynthesis offers a promising strategy for light-driven biomanufacturing, yet its efficiency remains limited by the non-selective conversion of photogenerated electrons into metabolically usable reducing power, causing energy dissipation and weak coupling between light capture and metabolic reactions. Here, we report a rational strategy using riboflavin (RF), a membrane-permeable and biocompatible flavin photosensitizer, to selectively channel photonic energy into intracellular NADPH regeneration. Quantum chemical calculations and spectroscopic analyses reveal that light-excited RF exhibits a specific binding affinity and favorable electron transfer trend toward NADP

Indexed as

NADPPhotosensitizing AgentsRiboflavinElectronsElectron TransportEnergy TransferOxidation-ReductionPhotosynthesisNADPPhotosensitizing AgentsRiboflavinbiocatalysiselectron transferenergy conversionmicrobial artificial photosynthesisNADPH regenerationriboflavinsynthetic biology

Identifiers

PMID42299068
PMCPMC13480618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.