Evidence map›Paper›PMID 42298729›Full record

ArticleAntimicrobial resistance and infection control2026

Development of indicators to evaluate the effectiveness of antimicrobial stewardship programs in Korea: a Delphi consensus study.

Sung Min Lim, Raeseok Lee, Jinnam Kim, Ji Young Park, Choseok Yoon, Myung Jin Lee, Song Mi Moon, Yong Chan Kim, Hong Bin Kim, Se Yoon Park and 1 more

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sung Min Lim *Department of Pediatrics, Hanyang University College of Medicine, Seoul, Republic of Korea.
Raeseok Lee *Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Jinnam KimDivision of Infectious Diseases, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul, Republic of Korea.
Ji Young ParkDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Choseok YoonDivision of Infectious Diseases, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul, Republic of Korea.
Myung Jin LeeDepartment of Internal Medicine, Inje University Sanggye-Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea.
Song Mi MoonDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
Yong Chan KimDepartment of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Hong Bin KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
Se Yoon ParkDivision of Infectious Diseases, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul, Republic of Korea. syparkmd@hanyang.ac.kr.
Bongyoung KimDivision of Infectious Diseases, Department of Internal Medicine, Hanyang University Seoul Hospital, Seoul, Republic of Korea. sobakas@hanyang.ac.kr.

Funding

by the Korea Disease Control and Prevention Agency Grant No: 2024-10-012HSRD VA SDR 10-012
6 · The paper itself

Abstract

backgroundA pilot program launched in November 2024 to establish and operationalize Antimicrobial Stewardship Programs (ASPs) in Korean hospitals is expected to accelerate nationwide adoption. However, consensus on indicators for evaluating ASP performance remains lacking. This study aimed to develop indicators for evaluating the short- and long-term effectiveness of ASPs.

methodsAn expert panel comprised 18 specialists from academic societies and government agencies involved in infectious diseases and antimicrobial control in South Korea. Candidate indicators for evaluating ASP effectiveness were identified by five infectious disease specialists through a systematic literature review. The Delphi survey consisted of an initial open-ended round, followed by two multiple-choice rounds (rounds 2 and 3) with an intervening online panel meeting. Responses to the multiple-choice questions were rated on a 7-point Likert scale, and indicators with a content validity ratio of ≥ 0.47 were selected.

resultsThe systematic literature review yielded 59 candidate indicators of ASP effectiveness, which were classified into seven primary categories. After the third-round Delphi survey, the final set of indicators included the following. In the Antibiotic Use Indicators category: (1) days of therapy per 1,000 patient-days, (2) defined daily dose per 1,000 patient-days, (3) reduction rate of broad-spectrum antibiotic use, (4) intravenous-to-oral antibiotic conversion rate, (5) reduction rate of unnecessary combination therapy, and 6) change in antibiotic prescription ratio according to the World Health Organization Access, Watch, and Reserve classification. In the Process-Related Indicators category: (1) appropriate rate of preoperative surgical antibiotic prophylaxis, (2) implementation of therapeutic drug monitoring with dosage recommendations, and (3) establishment of institutional antibiotic use guidelines. In the Department-Specific Indicators related to operating rooms and surgery: (1) appropriate rate of preoperative surgical antibiotic prophylaxis, (2) appropriateness of postoperative antibiotic discontinuation timing, and (3) appropriateness of prophylactic antibiotic selection. Finally, among the Other Indicators, the implementation rate of core ASP elements was selected as an indicator for evaluating ASP effectiveness.

conclusionsThis study established consensus-based indicators and proposed short- and long-term targets for evaluating the effectiveness of ASPs in Korea. These indicators enable standardized assessment and help inform evidence-based policies for the sustainable operation of ASPs.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipConsensusDelphi TechniqueHumansRepublic of KoreaAnti-Bacterial AgentsAntimicrobial stewardshipDelphi methodEvaluationIndicatorsRepublic of Korea

Identifiers

PMID42298729
PMCPMC13520494

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.