ArticleJournal of eating disorders2026
The association of vitamin D deficiency with depressive disorders in patients with eating disorders: a cross-sectional study.
Article in Journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundVitamin D deficiency and depressive disorders are both common in patients with eating disorders (EDs). However, the association between vitamin D status and current depressive disorder (CDD) in EDs populations remains insufficiently explored.
methodsWe conducted a cross-sectional study including 481 outpatients with EDs assessed at a specialized eating-disorders unit in Montpellier, France. Psychiatric diagnoses were established using the Mini-International Neuropsychiatric Interview (M.I.N.I.). Eating-disorder severity was assessed with the Eating Disorder Examination Questionnaire (EDE-Q). Serum 25-hydroxyvitamin D levels were measured as part of routine clinical assessment, and vitamin D deficiency was defined as < 20 ng/mL. Odds ratios (ORs) were estimated using logistic regression.
resultsVitamin D deficiency was significantly associated with higher odds of CDD (OR 1.98, 95% CI 1.20-3.28; p = 0.008). This association persisted after adjustment for EDs severity, psychiatric comorbidities, and season of assessment. No significant interactions were found between vitamin D deficiency and eating-disorder subtype, EDE-Q score, or season.
conclusionsVitamin D deficiency was associated with the presence of a current depressive disorder in patients with eating disorders, independently of EDs subtype, severity, and seasonality. These findings support the clinical relevance of assessing vitamin D status in patients with EDs presenting with depressive symptoms. Longitudinal studies are needed to clarify the direction and clinical implications of this association.
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