Evidence map›Paper›PMID 42298644›Full record

ArticleVeterinary research2026

Seroprevalence and associated risk factors for feline panleukopenia virus infection among managed giant pandas in China.

Yunli Li, Renyong Jia, Hongwen Zhang, Xin Chen, Jianhong Zeng, Jingchao Lan, Chanjuan Yue, Dongsheng Zhang, Wenjun Huang, Wanjing Yang and 5 more

Abstract read
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In one paragraph

Article in Veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yunli LiSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Renyong JiaCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Hongwen ZhangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Xin ChenSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Jianhong ZengSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Jingchao LanSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Chanjuan YueSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Dongsheng ZhangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Wenjun HuangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Wanjing YangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Xueyang FanSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Xianzhu XiaChinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Changchun, 130122, China.
Rong HouSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China.
Na FengChinese Academy of Agricultural Sciences, State Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Changchun, 130122, China. fengna0308@126.com.
Songrui LiuSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu Research Base of Giant Panda Breeding, Chengdu, 610081, China. srui_liu@163.com.

Funding

National Natural Science Foundation of China 2023YFF1305402the Research Project of Chengdu Research Base of Giant Panda Breeding 202503KY0001
6 · The paper itself

Abstract

Feline panleukopenia virus (FPV) poses a significant threat to carnivores worldwide, with increasing documentation of spillover infections in endangered species, including the giant panda (Ailuropoda melanoleuca). Despite the presence of serological evidence indicating historical exposure, contemporary data concerning the prevalence of FPV and the associated risk factors in giant pandas remains limited. This study conducted a comprehensive seroepidemiological survey of 136 giant pandas, representing 262 serum samples, from the Chengdu Research Base of Giant Panda Breeding between 2015 and 2023. The overall seroprevalence of FPV antibodies was 56.87% (149/262, 95% CI 0.51-0.63), with consistently high levels observed across years. Multivariate analysis identified young age and the summer season as protective factors, likely due to maternal-derived antibodies and environmentally mediated reduction in viral persistence, respectively. Although not statistically significant, a transfer history showed a trend toward elevated risk (OR > 1), suggesting that it may still represent a potential risk factor. It is important to note that current vaccination protocols appear to be inadequate in eliciting robust immune responses, thereby underscoring the necessity for the development of tailored vaccines. These findings emphasize the persistent and widespread circulation of FPV in captive giant pandas and advocate for seasonally targeted biosecurity measures, rationalized animal transfer protocols, and enhanced immunization strategies to mitigate infection risks in this vulnerable species.

Indexed as

Feline PanleukopeniaFeline Panleukopenia VirusUrsidaeAnimalsAntibodies, ViralChinaFemaleMalePrevalenceRisk FactorsSeasonsSeroepidemiologic StudiesAntibodies, ViralFeline panleukopenia virusgiant pandaseroprevalence

Identifiers

PMID42298644
PMCPMC13267628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.