Evidence map›Paper›PMID 42298614›Full record

ArticleIrish veterinary journal2026

Nationwide seroprevalence of paratuberculosis in indigenous Turkish goat breeds reveals extensive herd-level circulation and breed-associated risk.

Yalçın Yaman, Ahmet Eser, Devran Coşkun, Ramazan Aymaz, Yiğit Emir Kişi, Murat Keleş, Serdar Yağcı, Özgül Gülaydın, Serkan Süleyman Şengül, Kıvanç İrak and 1 more

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Article in Irish veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yalçın YamanFaculty of Veterinary Medicine, Siirt University, Siirt, TR-56100, Türkiye. yalcinyaman@gmail.com.
Ahmet EserFaculty of Veterinary Medicine, Siirt University, Siirt, TR-56100, Türkiye.
Devran CoşkunFaculty of Veterinary Medicine, Siirt University, Siirt, TR-56100, Türkiye.
Ramazan AymazDepartment of Breeding Techniques, Sheep Breeding Research Institute, Bandırma, Balıkesir, TR-10200, Türkiye.
Yiğit Emir KişiDepartment of Breeding Techniques, Sheep Breeding Research Institute, Bandırma, Balıkesir, TR-10200, Türkiye.
Murat KeleşDepartment of Breeding Techniques, Sheep Breeding Research Institute, Bandırma, Balıkesir, TR-10200, Türkiye.
Serdar YağcıDepartment of Livestock and Aquatic Products, General Directorate of Agricultural Research and Policies, Ankara, TR-06000, Türkiye.
Özgül GülaydınFaculty of Veterinary Medicine, Siirt University, Siirt, TR-56100, Türkiye.
Serkan Süleyman ŞengülDepartment of Breeding Techniques, Sheep Breeding Research Institute, Bandırma, Balıkesir, TR-10200, Türkiye.
Kıvanç İrakFaculty of Veterinary Medicine, Siirt University, Siirt, TR-56100, Türkiye.
Memiş BolacalıDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Kırşehir Ahi Evran University, Kırşehir, TR-40100, Türkiye.

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu TOVAG-222O107
6 · The paper itself

Abstract

Paratuberculosis (Johne's disease), caused by Mycobacterium avium subsp. paratuberculosis (MAP), imposes substantial veterinary burdens globally, with potential zoonotic implications, yet systematic surveillance in Turkish goat populations has been poorly documented. This study presents the first national, multi-breed cross-sectional serosurvey of MAP infection across seven indigenous Turkish goat breeds (n = 3,372; 36 herds; 11 provinces), employing a commercial indirect ELISA and modified Poisson regression with robust variance estimation to generate prevalence ratios (PRs) directly interpretable as relative risks. Overall apparent seroprevalence reached 14.07% (95% CI: 12.83-15.31%), with herd-level positivity of 93.5%-establishing endemic dissemination across geographically and climatically diverse production systems. Breed-level seroprevalence spanned a 2.66-fold gradient (8.45%-22.47%). Four breeds showed significantly elevated adjusted PRs: Colored Angora (PR = 2.702), Turkish Saanen (PR = 2.571), Maltese (PR = 2.027), and Honamlı (PR = 1.469); three retained significance under cluster-robust estimation. The intraclass correlation coefficient (ICC = 0.031) indicated low within-herd clustering, suggesting that individual-level factors may contribute more to seroconversion outcome than shared herd environment in this dataset. Population attributable fraction analysis identified Turkish Saanen (19.70%) and Maltese (13.77%) as the dominant drivers of national disease burden. The seroprevalence contrast between White Angora (0%) and Colored Angora (22.47%) warrants controlled investigation of differential exposure, management, and potentially breed-specific factors. These findings provide an evidence base for establishing a national MAP control programme for small ruminants in Türkiye.

Indexed as

ELISAIndigenous goat breedsJohne’s diseaseMAPModified Poisson regressionParatuberculosisPopulation attributable fractionPrevalence ratioSeroprevalenceTurkiye

Identifiers

PMID42298614
PMCPMC13508357

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.