Evidence map›Paper›PMID 42298588›Full record

ArticleCritical care (London, England)2026

Evaluating possible treatment effect heterogeneity in a randomized trial of milrinone versus dobutamine in cardiogenic shock.

Lucas L Marinho, Gabriele Lileikyte, Philippe Boileau, Ying Lu, Matthew Churpek, Alexandra Spicer, Michael Harhay, Zhe Chen, Adriana Luk, Fernando G Zampieri and 12 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Lucas L MarinhoMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada.
Gabriele LileikyteDepartment of Clinical Sciences Helsingborg, Anaesthesia and Intensive Care, Lund University, Skåne University Hospital, Malmö, Sweden.
Philippe BoileauMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada.
Ying LuMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada.
Matthew ChurpekDepartment of Medicine, University of Wisconsin-Madison, Madison, USA.
Alexandra SpicerDepartment of Medicine, University of Wisconsin-Madison, Madison, USA.
Michael HarhayDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhe ChenDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Adriana LukUniversity of Toronto, Toronto, Canada.
Fernando G ZampieriDepartment of Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.
Caio A M TavaresAcademic Research Organization, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Alastair ProudfootDepartment of Perioperative Medicine, Barts Heart Centre, Barts Health NHS Trust, London, England; Critical Care & Perioperative Medicine Research Group, Queen Mary University, London, England.
Cristina PopMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada.
Patrick J F DeschênesMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada.
Ryan ZarychanzkiDepartment of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Sylvain LotherDepartment of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Ludhmila Abrahão HajjarEmergency and Intensive Care, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Jacob C JentzerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Sean van DiepenDepartment of Critical Care Medicine, Divisions of Cardiology, Department of Medicine, University of Alberta, Edmonton, Canada.
Pietro di SantoDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Rebecca MathewCAPITAL Research Lab, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Patrick R LawlerMcGill University Health Centre, McGill University, 1001 boulevard Décarie, Montreal, H4A 3J1, Canada. patrick.Lawler@mcgill.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42298588
PMCPMC13267396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.