ArticleBMC oral health2026
Carbon nanotube‑ and hydroxyapatite‑coated implants: histomorphometric assessment in a rabbit model.
Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
objectiveThis study aimed to investigate whether the integration of functionalized carbon nanotubes (CNTs) with hydroxyapatite (HA) could create a bioactive nanocomposite capable of enhancing the early stages of osseointegration. Specifically, we investigated whether the high surface area and nanoscale structure of CNTs, combined with the osteoconductivity of 1% HA, could significantly enhance bone-to-implant contact (BIC) and new bone area (NBA) compared to traditional titanium surfaces in a mandibular model.
methodsHere we evaluated the osseointegration of titanium implant discs coated with CNTs and CNTs combined with 1% HA in a rabbit mandibular model. Thirty rabbits received uncoated, CNT-coated, or CNT- HA coated titanium discs implanted into mandibular defects. After 4 weeks, bone-to-implant contact (BIC) and new bone area (NBA) were assessed histomorphometrically.
resultsBoth CNT and CNT- HA coatings significantly increased BIC and NBA compared to uncoated implants (p < 0.05), with no significant difference between coated groups.
conclusionCNT-based coatings enhance early osseointegration of titanium implants, while the addition of 1% HA does not confer additional benefit within 4 weeks, suggesting CNT coatings alone may improve implant integration effectively.
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