Evidence map›Paper›PMID 42298523›Full record

ArticleBMC surgery2026

Evaluation and prevalence of associated anomalies in children with anorectal malformations at a tertiary referral center.

Mahshad Maadani, Bahar Ashjaei, Hojjatollah Raji, Mahboobeh Bahroudi, Mastaneh Moghtaderi

Abstract read
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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mahshad MaadaniCardiovascular Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.ORCID http://orcid.org/0000-0002-2438-4876
Bahar AshjaeiDepartment of Pediatric Surgery, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-7767-815X
Hojjatollah RajiDepartment of Pediatric Surgery, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahboobeh BahroudiPediatric Chronic Kidney Disease Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Hospital, Tehran University of Medical Sciences, Dr. Qarib St, Tehran, Iran.ORCID http://orcid.org/0000-0001-5948-9515
Mastaneh MoghtaderiPediatric Chronic Kidney Disease Research Center, Gene, Cell and Tissue Research Institute, Children's Medical Center Hospital, Tehran University of Medical Sciences, Dr. Qarib St, Tehran, Iran. Drmoghtaderi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnorectal malformations (ARMs) comprise a spectrum of congenital anomalies frequently associated with multisystem congenital defects. Early recognition of associated anomalies is essential for appropriate surgical planning and long-term management. This study aimed to investigate the prevalence of associated anomalies with ARMs in the Children's Tertiary Center. MATERIALS AND

methodsThis retrospective cross-sectional study included all children diagnosed with ARM who were admitted to the Children's Medical Center Hospital between 2020 and 2022. Associated anomalies were categorized by organ system and by syndromic patterns, including VACTERL association. Data were extracted from medical records. Descriptive statistics were used, and associations with sex and gestational age were analyzed using Chi-square or Fisher's exact tests.

resultsFifty-seven children with ARM were included (52.6% male). Associated anomalies were detected in 73.7% of patients. The most common associated anomalies involved the cardiovascular (52.6%), genitourinary (36.8%), and vertebral (24.6%) systems. No significant association was found between gestational age and the prevalence of anomalies. Female sex was associated with a higher prevalence of cardiac anomalies.

conclusionAssociated anomalies are highly prevalent in children with ARM, particularly affecting the cardiovascular, genitourinary, and vertebral systems. Systematic screening and multidisciplinary management are essential to reduce morbidity and improve long-term outcomes.

Indexed as

Abnormalities, MultipleAnorectal MalformationsHeart Defects, CongenitalAnal CanalChildChild, PreschoolCross-Sectional StudiesEsophagusFemaleHumansInfantInfant, NewbornKidneyLimb Deformities, CongenitalMalePrevalenceAnorectal malformationAssociated malformationsImperforate anusVACTERL

Identifiers

PMID42298523
PMCPMC13495381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.