ArticleBMC pediatrics2026
Are there other undiagnosed tick-borne infections in children being evaluated for Lyme neuroborreliosis?
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Establishment and application of a multiplex qPCR panel for multi-host surveillance of tick-Borne pathogens.Emerging microbes & infections · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is an increasing amount of reported clinical cases of emerging tick-borne diseases (eTBDs) such as human granulocytic anaplasmosis, neoehrlichiosis, babesiosis and rickettsiosis. The incidence of eTBDs in children is rather unknown, potentially due to low awareness regarding these diseases among health professionals. The clinical picture may be unspecific and access to laboratory tests limited. We aimed to investigate the incidence and clinical manifestations of eTBDs, including possible co-infections, within a pediatric patient group evaluated for Lyme neuroborreliosis (LNB).
methodsIn a cohort of Swedish children being evaluated for LNB (n = 235) during 2011-2014, samples and data on clinical manifestations and laboratory findings were prospectively collected. Plasma samples were analysed by real-time polymerase chain reaction (PCR) for detection of Anaplasma phagocytophilum, Neoehrlichia mikurensis, Babesia species (spp.) and Rickettsia spp. Cerebrospinal fluid from a subset of the patients was also analysed for Rickettsia spp. by real-time PCR.
resultsNo evidence of eTBDs, nor tick-borne co-infections, was found in the analysed samples from children evaluated for LNB.
conclusionsWe conclude that no evidence for potential eTBDs was found within a Swedish pediatric patient group with potential high exposure to tick-borne pathogens. However, given the indications of the emergence of ticks and several tick-borne pathogens, we suggest that eTBDs should be considered as differential diagnoses in patients with non-LNB, atypical LNB or unexplained fever and skin rashes, including a complete blood count and liver enzymes in the diagnostic workup.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.