ArticleBMC pregnancy and childbirth2026
Proportion and risk factors of retinal changes in pregnant women with HELLP syndrome.
Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsTo report the proportion and risk factors associated with retinal changes in Chinese pregnant women diagnosed with HELLP syndrome.
methodsA retrospective review of medical records was conducted for all pregnant women with HELLP syndrome delivered at the Second Affiliated Hospital of Wenzhou Medical University between September 2010 and August 2023. Retinal changes were identified and were categorized into retinal vascular changes and serous retinal detachment based on the ophthalmology consultation records. The proportion of retinal changes was calculated, and associated risk factors were analyzed.
resultsA total of 70 cases with HELLP syndrome were included, with a mean age of 30.1 ± 5.2 years. Forty-nine cases received ophthalmology consultation, presenting a consultation rate of 70.0%. The proportion of retinal changes was 55.1% (27/49) in cases with HELLP syndrome. The proportion of retinal vascular changes and serous retinal detachment were 30.6% (15/49) and 24.5% (12/49), respectively. Patients with retinal vascular change (120.7 ± 8.0 mmHg) and those with serous retinal detachment (116.7 ± 14.5 mmHg) demonstrate significantly elevated diastolic blood pressure at the time of HELLP syndrome diagnosis compared to case without retinal changes (110.1 ± 12.4 mmHg, P = 0.032). HELLP syndrome cases treated with corticosteroids were more likely to develop serous retinal detachment compared to those not receiving corticosteroids (40.0% vs. 13.8%, P = 0.040).
conclusionThe proportion of retinal changes was 55.1% among Chinese pregnant women with HELLP syndrome. Elevated diastolic blood pressure was identified as associated risk factor for developing retinal changes. The use of corticosteroids may have more risk of developing serous retinal detachment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.