Trial reportBMC anesthesiology2026
High-flow nasal oxygen versus conventional nasal cannula for gastroscopy with sedation in elderly patients at high altitudes: a partially-blinded randomized controlled trial in Tibet, China.
Trial report in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
9 authors.
Funding
Abstract
backgroundIn high-altitude environments with hypobaric hypoxia, chronic hypoxia can affect organs. This study aimed to determine whether high-flow nasal oxygen (HFNO) can reduce the incidence of hypoxemia in elderly patients undergoing gastroscopy with sedation at high altitudes.
methodsThis single-center, partially-blinded, prospective randomized trial was conducted in Shigatse, Tibet, China (3800 m above sea level). Elderly patients aged ≥ 60 undergoing gastroscopy with sedation were randomly assigned to either the HFNO group (60 L per minute, 100% oxygen) or the conventional nasal cannula (CNC) group (6 L per minute). The primary endpoint was the incidence of hypoxemia, defined as pulse SpO
resultsThe incidence of hypoxemia was significantly lower in the HFNO group than the CNC group (2.8% vs. 32.9%, risk ratio (RR): 0.691; 95% confidence interval (CI): 0.584-0.818, p < 0.001). The median SpO
conclusionsCompared to CNC, HFNO significantly reduced the incidence of hypoxemia during gastroscopy with sedation in elderly patients at high altitudes.
trial registrationChiCTR2400085110; registered on 31 May 2024.
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