Evidence map›Paper›PMID 42298281›Full record

ArticleSpine deformity2026

Proximal junctional failure combined with symptomatic thoracic disc herniation: a rare case report.

Xuejun Zhang, Lukas Klein, Nils Mühlenfeld, Oliver Huwert, Frank Hassel

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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Xuejun ZhangDepartment of Spine Surgery, Loretto Study Group, Loretto-krankenhaus Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-1866-369X
Lukas KleinDepartment of Spine Surgery, Loretto Study Group, Loretto-krankenhaus Freiburg, Freiburg, Germany.
Nils MühlenfeldDepartment of Orthopedics and Trauma Surgery, Medical Center-Albert-Ludwigs-University of Freiburg, Freiburg, Germany.
Oliver HuwertDepartment of Spine Surgery, Loretto Study Group, Loretto-krankenhaus Freiburg, Freiburg, Germany.
Frank HasselDepartment of Spine Surgery, Loretto Study Group, Loretto-krankenhaus Freiburg, Freiburg, Germany. frank.hassel@artemed.de.ORCID http://orcid.org/0000-0001-5618-9285

Funding

Chinese Government Scholarship
6 · The paper itself

Abstract

purposeTo report a complex case of proximal junctional failure (PJF) associated with acute thoracic disc herniation (TDH) in the mid-thoracic spine following thoracolumbar fusion.

methodsCase report.

resultsA 74-year-old female with osteoporosis and rheumatoid arthritis underwent multiple spinal fusion and revision surgeries, culminating in a T9-S1 fusion. Two months following the third revision, she developed PJF. Seven months following the third revision, she presented with severe pain and progressive sensory loss in both lower extremities (predominantly left side). Neurological examination revealed incomplete paraparesis (AIS grade C). While initial cervical MRI findings were unremarkable, thoracic imaging demonstrated a T8 vertebral fracture and a significant T8/9 disc herniation causing spinal stenosis. The patient underwent T5-S1 revision surgery, including T8 laminectomy and sequestrectomy. Seven months after the fourth revision surgery, her neurological function improved significantly to AIS grade E, with significant pain relief.

conclusionPJF may precipitate acute intervertebral disc herniation due to excessive biomechanical stress at the adjacent mobile segment. Early restoration of sagittal alignment and proactive spinal stabilization are crucial for protecting spinal cord function.

Indexed as

Case reportProximal junctional failureProximal junctional kyphosisThoracic disc herniationThoracolumbar fusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.