ArticleEJNMMI radiopharmacy and chemistry2026
Preclinical evaluation of a fluorine-18-labeled indocyanine green analog for PET imaging of hepatic function.
Article in EJNMMI radiopharmacy and chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAccurate assessment of liver function and biliary excretion is a key aspect in the medical and surgical management of various liver conditions. Dynamic nuclear imaging techniques such as PET (positron emission tomography) offer the potential to directly quantify hepatic clearance and hepatobiliary function. Indocyanine green (ICG) is a fluorescent dye that is used to indirectly evaluate liver function via its plasma clearance, but its optical properties preclude deep tissue imaging. Here, we report the synthesis and preclinical evaluation of a novel fluorine-18 labeled ICG derivative ([
resultsICG was successfully labeled with
conclusionsThis study presents [
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