Evidence map›Paper›PMID 42298160›Full record

ArticleAesthetic plastic surgery2026

Integrated Management of Mycobacterium abscessus Infections Following Aesthetic Fat Grafting: A Promising Combination of Targeted Medication and Minimally Invasive Surgery.

Zhengjie Lin, Zhijing Chen, Yangcheng Hu, Danyi Weng, Jianfeng Huang, Dane Lin, Danyi Lin

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengjie Lin *Department of Pathology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, People's Republic of China.
Zhijing Chen *Department of Medical Cosmetic Center, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.
Yangcheng HuDepartment of Urology, Shantou Central Hospital, Shantou, 515031, People's Republic of China.
Danyi WengDepartment of Nephrology, Shantou Chaonan Minsheng Hospital, Shantou, 515144, People's Republic of China.
Jianfeng HuangDepartment of Pediatrics, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China. 1076101404@qq.com.
Dane LinDepartment of Neonatal Intensive Care Unit, Department of Pediatrics, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China. m13715870419@163.com.
Danyi LinDepartment of Pathology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, People's Republic of China. danyi_l@126.com.

Funding

Guangdong Provincial Administration of Traditional Chinese Medicine Project 20251008
6 · The paper itself

Abstract

backgroundInfections caused by nontuberculous mycobacteria (NTM), particularly Mycobacterium abscessus, represent rare but increasingly reported complications following cosmetic fat transplantation. However, standardized and effective treatment protocols remain underexplored. This study aimed to evaluate the efficacy of anti-tuberculosis (anti-TB) medication combined with local vacuum aspiration in treating multiple wound infections caused by Mycobacterium abscessus complex following autologous fat transplantation.

methodsBetween June 2017 and June 2019, 10 patients with M. abscessus complex infection after autologous fat grafting were enrolled, involving a total of 70 infected wounds (31 facial, 32 breast, and 7 thigh sites). Prior to minimal-incision open debridement, ultrasound localization was performed. Necrotic granulation tissue was thoroughly curetted, followed by vacuum sealing drainage (VSD) with continuous aspiration. Irrigation and drainage tubes were subsequently placed to promote granulation tissue formation. All patients received standardized anti-TB drug therapy.

resultsDuring a follow-up period ranging from 8 to 16 months (mean: 12 months), all 70 wounds in the 10 enrolled patients achieved satisfactory healing in terms of both deep tissue repair and superficial appearance. No recurrence of infection was observed throughout the follow-up period. Wound closure was accomplished without the need for additional surgical reconstruction in all cases. The combination of anti-TB chemotherapy and vacuum aspiration consistently promoted granulation tissue formation and controlled local inflammation, leading to functionally and cosmetically acceptable outcomes across all anatomical sites, including face, breast, and thigh regions.

conclusionThe combination of minimal-incision debridement, local vacuum aspiration, and anti-TB medication provides an effective and practical treatment for M. abscessus infections secondary to autologous fat grafting. This integrated approach is recommended for managing such challenging postoperative infections. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Adipose TissueAntitubercular AgentsMycobacterium abscessusMycobacterium Infections, NontuberculousSurgical Wound InfectionAdultCohort StudiesCombined Modality TherapyDebridementFemaleFollow-Up StudiesHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresTransplantation, AutologousAntitubercular AgentsAnti-TB drugsAutologous fat fillingInfected woundMycobacterium abscessus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.