Evidence map›Paper›PMID 42298151›Full record

ArticleCommunications biology2026

Efficient recovery of zebrafish maternal-zygotic mutants from in vivo expanded and cryopreserved germline stem cells.

Yaqing Wang, Rui Qu, Xiaosi Wang, Yongkang Hao, Jiajie Deng, Houpeng Wang, Yonghua Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaqing WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Rui QuSchool of Marine Biology and Fisheries, Hainan University, Haikou, China.
Xiaosi WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China. wangxs@ihb.ac.cn.ORCID 0000-0002-7950-5997
Yongkang HaoState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jiajie DengState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Houpeng WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yonghua SunState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Hubei Hongshan Laboratory, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China. yhsun@ihb.ac.cn.ORCID 0000-0001-9368-6969

Funding

China Postdoctoral Science Foundation 2023M733699National Natural Science Foundation of China (National Science Foundation of China) 32025037 and 32403020
6 · The paper itself

Abstract

Long-term preservation of genetic lines is crucial for animal research. Current methods heavily rely on cryopreservation of haploid sperm, whereas diploid germline stem cells (GSCs) may provide a superior alternative. Here, using zebrafish, we establish an integrated platform combining in vivo expansion of GSCs (eGSCs), cryopreservation and direct genetic recovery. The eGSCs are amplified in cyp11a2

Indexed as

CryopreservationGerm CellsMutationStem CellsZebrafishZygoteAnimalsAnimals, Genetically ModifiedFemaleMaleZebrafish ProteinsZebrafish Proteins

Identifiers

PMID42298151
PMCPMC13631277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.