Evidence map›Paper›PMID 42298114›Full record

ReviewNature reviews. Neurology2026

Psychological interventions for migraine.

Licia Grazzi, Paul B Rizzoli, Danilo Antonio Montisano, Giorgio Lambru, Alberto Raggi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Licia GrazziHeadache Center, Department of Neuroalgology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy. licia.grazzi@istituto-besta.it.ORCID http://orcid.org/0000-0001-6535-1109
Paul B RizzoliDepartment of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Danilo Antonio MontisanoHeadache Center, Department of Neuroalgology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.ORCID http://orcid.org/0000-0003-4834-2045
Giorgio LambruHeadache and Facial Pain Service, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0002-2780-4776
Alberto RaggiNeurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.ORCID http://orcid.org/0000-0002-7433-7779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is a complex condition that imposes substantial epidemiological impact and social burden. In the past decade, innovative and targeted pharmacological preventive therapies have considerably improved the lives of people with migraine. A biopsychosocial model has been proposed to comprehensively explain migraine complexity, shedding light on the interconnections between emotional, psychological, social and biological factors, in contrast to a strict medical model. This modern view recognizes that relying solely on pharmacological treatment might not be sufficient, and that alternative treatment options, in particular, psychological ones, should be considered to help individuals manage the condition and enhance the effectiveness of medications. In this Review, we describe the most relevant psychological interventions for migraine, namely relaxation training, biofeedback, cognitive behavioural therapy, mindfulness, and acceptance and commitment therapy, as well as patient education as a first step of care. We discuss how these interventions can assist individuals throughout their treatment journey and consider possible mechanisms of action and barriers to their implementation. Last, we conclude by presenting the possibilities offered by digital health interventions.

Indexed as

Migraine DisordersPsychosocial InterventionBiofeedback, PsychologyCognitive Behavioral TherapyHumansMindfulnessRelaxation Therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.