ArticlePediatric research2026
Nutritional screening predicts prolonged stay in LMIC pediatric oncology settings: SCAN validation in Brazilian children.
Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Progressive deterioration in dietary intake and nutritional risk during oncological treatment in children with solid tumors: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
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6 authors.
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Abstract
backgroundMalnutrition affects 50-90% of children with cancer in low- and middle-income countries (LMICs) and worsens clinical outcomes. The Nutrition Screening Tool for Childhood Cancer (SCAN) is cancer-specific but has not been validated in Brazilian Portuguese. We aimed to evaluate the diagnostic accuracy of the Brazilian Portuguese SCAN (SCAN pt-BR) against STRONGkids and to examine its association with prolonged hospitalization and ICU admission.
methodsProspective diagnostic-accuracy study at a tertiary pediatric oncology center in Brazil (February-December 2021). Consecutive inpatients aged 1-18 years with expected stay ≥48 h were screened within 24-48 h of admission by pediatric dietitians using SCAN pt-BR and STRONGkids.
resultsOf 262 children (median age 8.8 years, 52.7% male, 41.2% hematologic malignancies), 70.2% were classified as at risk by SCAN pt-BR. Against STRONGkids ≥4, SCAN showed sensitivity 94.6%, specificity 43.2%, and ROC-AUC 0.863. SCAN risk independently predicted prolonged stay (adjusted OR 2.33, 95% CI 1.29-4.30, p = 0.006) but not ICU admission (adjusted OR 0.96, p = 0.899).
conclusionSCAN pt-BR showed adequate screening performance and independently predicted prolonged hospitalization in Brazilian children with cancer. These results support its use for admission nutritional triage in LMIC pediatric oncology settings. IMPACT: SCAN identified 70.2% of children as at nutritional risk and predicted prolonged hospitalization (adjusted OR 2.33, 95% CI 1.29-4.30) independently of age, tumor group, and STRONGkids classification. Against STRONGkids high-risk classification, SCAN pt-BR showed high sensitivity (94.6%), high negative predictive value (93.6%), and ROC-AUC of 0.863. Gastrointestinal symptoms, poor oral intake, and recent weight loss were the most frequently endorsed symptom-related items that children classified as at nutritional risk, suggesting that SCAN detects acute nutritional deterioration rather than static disease characteristics. Routine application at admission could direct early dietetic referral to children most likely to require prolonged inpatient care.
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