Evidence map›Paper›PMID 42297984›Full record

ReviewDiscover nano2026

Highly cited original research in microneedle science from 2015 to 2025 a bibliometric and altmetric analysis.

Xuanrui Chen, Qian Zhang, Changbin Zhao, Guangbin Wang, Hailing Ren, Mingjing Yang, Shihui Liu, Tao Liu, Bin Guo

Abstract readReview
In one paragraph

Review in Discover nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuanrui ChenMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Qian ZhangKey Laboratory of Dryness Syndrome in Chinese Medicine, Ministry of Education, Ningxia Regional Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Regional High Incidence Disease, Ningxia Medical University, Yinchuan, China.
Changbin ZhaoKey Laboratory of Dryness Syndrome in Chinese Medicine, Ministry of Education, Ningxia Regional Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Regional High Incidence Disease, Ningxia Medical University, Yinchuan, China.
Guangbin WangKey Laboratory of Dryness Syndrome in Chinese Medicine, Ministry of Education, Ningxia Regional Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Regional High Incidence Disease, Ningxia Medical University, Yinchuan, China.
Hailing RenKey Laboratory of Dryness Syndrome in Chinese Medicine, Ministry of Education, Ningxia Regional Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Regional High Incidence Disease, Ningxia Medical University, Yinchuan, China.
Mingjing YangMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Shihui LiuMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Tao Liu *Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, Guangzhou, China. lt045021@gzucm.edu.cn.
Bin Guo *Key Laboratory of Dryness Syndrome in Chinese Medicine, Ministry of Education, Ningxia Regional Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Regional High Incidence Disease, Ningxia Medical University, Yinchuan, China. Guo12200055@163.com.

Funding

Ningxia Hui Autonomous Region Health Science and Technology Research Project 2026-NWZD-A012the 2023 Key Research and Development Program of Yanchi County 2023YCYDCT003the National Natural Science Foundation of China Regional Science Fund No. 82460972the Ningxia Hui Autonomous Region Key R&D Program 2026BEG02031the Ningxia Natural Science Foundation 2025AAC040009
6 · The paper itself

Abstract

This study comprehensively analyzes the top 100 highly cited publications in microneedle (MN) research to reveal convergences and divergences in academic and public interest, assess the current research landscape and its impact, and offer data-driven support for clarifying future research directions.We identified highly cited microneedle articles published from 2015 to July 15, 2025 using the Web of Science database, validated the records through Scopus and Google Scholar, and gathered Altmetric attention scores from Altmetric.Extracted data encompassed citation counts, publication years, journals, authors, affiliations, and countries, which we summarized using descriptive statistics and visualized with CiteSpace, VOSviewer, and R for correlation analysis.From 8502 documents, the top 100 most-cited original research articles were selected. These articles appeared in 43 English-language journals and accrued 23,838 citations. The highest annual output occurred in 2020, with 18 publications and 4172 citations, while the top 10 journals together accounted for more than 60% of the highly cited articles. Zhen Gu authored the most articles (18), and the University of North Carolina at Chapel Hill led all institutions with 17 contributions.Our analysis suggests that microneedle research has expanded beyond conventional transdermal delivery into a diverse technological ecosystem encompassing clinical therapy, immunomodulation, smart diagnostics and therapeutics, and material sustainability. Among the most-cited microneedle articles in this analysis, Altmetric Attention Scores and citation metrics captured distinct dimensions of influence, with the former correlating more strongly with news and social media dissemination than with traditional citation counts. This divergence indicates a partial disconnect between public visibility and scholarly impact in the field.

Indexed as

AltmetricBibliometricCitation analysisMicroneedle

Identifiers

PMID42297984
PMCPMC13269640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.