Evidence map›Paper›PMID 42297811›Full record

ReviewNPJ biofilms and microbiomes2026

From diet to function: using synthetic microbial communities to map gut microbial interactions.

Dodzi Kwaku Jnr Senoo, Luke Acton, Lindsay J Hall

Abstract readReview
PubMed Publisher
In one paragraph

Review in NPJ biofilms and microbiomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dodzi Kwaku Jnr SenooDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK. dks463@student.bham.ac.uk.
Luke ActonDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK. l.j.acton@bham.ac.uk.
Lindsay J HallDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK. l.hall.3@bham.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/Y011619/1; BB/X011054/1Wellcome Trust 220876/Z/20/Z
6 · The paper itself

Abstract

Diet shapes gut microbial ecology and function, but causal mechanisms are hard to resolve in native communities. Synthetic microbial communities provide defined systems to test how dietary substrates alter community structure, metabolism, and host responses. This review summarises SynCom design, experimental platforms, and dietary applications, highlights multi-omics and modelling approaches, proposes reporting standards, and considers challenges and future directions, including multi-kingdom and AI-enabled function-first SynComs.

Indexed as

DietGastrointestinal MicrobiomeMicrobial InteractionsSynthetic BiologyAnimalsHumansMultiomics

Identifiers

PMID42297811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.