Evidence map›Paper›PMID 42297636›Full record

ArticleEnvironmental microbiology2026

New Finnlakevirus Isolate FLiP-2 Provides Insight Into the Ecology of ssDNA Phages in Flavobacterium Hosts.

Kati Mäkelä, Elina Laanto, Reetta Penttinen, Janne Ravantti, Kim Kreuze, Lotta-Riina Sundberg

Abstract read
In one paragraph

Article in Environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kati MäkeläDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.ORCID https://orcid.org/0000-0001-5574-9738
Elina LaantoDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.ORCID https://orcid.org/0000-0003-4172-3128
Reetta PenttinenDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.ORCID https://orcid.org/0000-0003-2152-9889
Janne RavanttiMolecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-8578-7230
Kim KreuzeHelsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0009-0009-8354-1163
Lotta-Riina SundbergDepartment of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland.ORCID https://orcid.org/0000-0003-3510-4398

Funding

Emil Aaltosen Säätiö #200260European Research Council 101117204OLVI-Säätiö #201910409Research Council of Finland #346772Research Council of Finland #354982Suomalainen Konkordia-liitto #20200077
6 · The paper itself

Abstract

Life cycle details or ecological impact are well characterized only for a few ssDNA phages. The Finnlakeviridae family includes one species, Finnlakevirus FLiP. Here, using the same Flavobacterium host and sampling location, we isolated a new strain designated FLiP-2, with 96.7% genetic identity to the original isolate FLiP. To understand the ecology of this Flavobacterium-infecting phage species, we explored the host interactions of the two FLiP strains and a dsDNA Flavobacterium phage MaF61 under various conditions representing those encountered in their natural habitats in boreal lakes including different temperatures, anoxic conditions, and in the presence of different nutrients and antibiotics. While FLiP and FLiP-2 had similar virion stability outside the host, they exhibited significant differences in plaque morphology and infectivity. FLiP-2 could not replicate in the presence of ampicillin, whereas FLiP thrived even at high concentrations. Both strains of Finnlakevirus FLiP propagated better under or after stress exposure compared to MaF61. Additionally, Finnlakevirus FLiP plaques appeared far from the original infection site, particularly in response to stress, suggesting non-lytic presence within a motile or filamentous bacterium. In conclusion, Finnlakevirus FLiP showed remarkable flexibility in host-interactions being well adapted to fluctuating conditions in boreal freshwaters.

Indexed as

BacteriophagesDNA, Single-StrandedDNA VirusesFlavobacteriumDNA, ViralLakesDNA, Single-StrandedDNA, Viralbacteriophageflavobacteriumphage ecologyphage–host interactionsssDNA phage

Identifiers

PMID42297636
PMCPMC13269007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.