Evidence map›Paper›PMID 42297407›Full record

GuidelineClinical and experimental emergency medicine2026

2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 4. Adult advanced life support.

Tae-Youn Kim, Gyo Jin Ahn, Kyoung-Chul Cha, Dong-Hyeok Kim, Youdong Sohn, Young Song, Gyuhong Shim, Do Kyun Kim, Yunhee Oh, Jin Wi and 16 more

Abstract readGuideline
In one paragraph

Guideline in Clinical and experimental emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Tae-Youn KimDepartment of Emergency Medicine, Inha University College of Medicine, Incheon, Korea.
Gyo Jin AhnDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Kyoung-Chul ChaDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Dong-Hyeok KimDivision of Cardiology, Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Youdong SohnDepartment of Emergency Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Young SongDepartment of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Gyuhong ShimDepartment of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea.
Do Kyun KimDepartment of Emergency Medicine, Seoul National University College of Medicine, Seoul, Korea.
Yunhee OhDesign and Contents Team, Asan Medical Center, Seoul, Korea.
Jin WiDivision of Cardiology, Gachon University College of Medicine, Incheon, Korea.
Chun Song YounDepartment of Emergency Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Myung-Lyeol LeeDepartment of Paramedicine, Baekseok University, Cheonan, Korea.
Mi Jin LeeDepartment of Emergency Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Byung Kook LeeDepartment of Emergency Medicine, Chonnam National University Medical School, Gwangju, Korea.
Byung Heon LeeEmergency Medical Center, Gangnam Severance Hospital, Seoul, Korea.
Jisook LeeDepartment of Emergency Medicine, Ajou University School of Medicine, Suwon, Korea.
Chang Hee LeeDepartment of Paramedicine, Namseoul University, Cheonan, Korea.
Hannah LeeDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Youngbin JangDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
Yong Soo JangDepartment of Emergency Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Young Hwa JungDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Woo Jin JungDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Sung Phil ChungDepartment of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
Gyu Chong ChoDepartment of Emergency Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Ju Sun HeoDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Sung Oh HwangDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.

Funding

Korea Disease Control and Prevention Agency 2024100BE7B-00Korean Association of Cardiopulmonary Resuscitation
6 · The paper itself

Abstract

The 2025 Korean advanced life support guidelines were updated using a structured evidence evaluation process informed by recent randomized controlled trials and systematic reviews. The guideline development group prioritized patient-important outcomes and assessed the certainty of the evidence to formulate graded recommendations. For drug administration during adult cardiac arrest, intravenous access is the preferred initial route, with intraosseous access recommended when intravenous access cannot be rapidly established. Epinephrine remains the recommended vasopressor. Routine administration of vasopressin, either alone or in combination with corticosteroids, is not recommended for in-hospital or out-of-hospital cardiac arrest. In the absence of specific indications, the routine use of buffering agents and calcium is discouraged owing to insufficient evidence of their benefits and potential harm. Defibrillation recommendations were refined based on emerging evidence. In adults with refractory ventricular fibrillation or pulseless ventricular tachycardia after multiple unsuccessful defibrillation attempts, vector change or double sequential defibrillation may be considered in selected settings when performed by experienced teams with appropriate equipment. Airway management guidelines recommend cricothyroidotomy as a rescue technique when conventional airway management strategies fail. For patients receiving cardiopulmonary resuscitation while on mechanical ventilation, specific ventilator settings during chest compressions are recommended to optimize ventilation and minimize interference with high-quality cardiopulmonary resuscitation. The guidelines also address cardiopulmonary resuscitation-induced consciousness, allowing the cautious use of sedatives and/or analgesic agents when awareness interferes with resuscitation quality or safety. Overall, the guidelines emphasize evidence-based practice and individualized clinical decision-making.

Indexed as

Advanced life supportCardiopulmonary resuscitationHeart arrest

Identifiers

PMID42297407
PMCPMC13277415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.