ArticleInfection2026
Clinical characteristics, antimicrobial susceptibility, and predictors of mortality in Streptococcus suis infection: a retrospective cohort study.
Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStreptococcus suis is an important zoonotic pathogen associated with severe disease and mortality. Reduced antimicrobial susceptibility has been increasingly reported. This study aimed to investigate the clinical characteristics, factors associated with mortality, and antimicrobial susceptibility of S. suis infections at a tertiary care hospital in Thailand.
methodsA retrospective cohort study was conducted among patients with S. suis infection between 2021 and 2025. Clinical characteristics, treatment outcomes, and antimicrobial susceptibility were collected. Multivariate logistic regression was used to identify factors associated with mortality.
resultsA total of 87 patients (90 infection episodes) were included. Meningitis (37.8%) and endocarditis (26.7%) were the most common presentations. The in-hospital mortality rate was 11.1%, similar to the 14-day mortality rate (10.0%). Susceptibility testing showed that 34.48% of isolates were susceptible to penicillin, 82.35% to ceftriaxone, and 100% to vancomycin. Septic shock was independently associated with increased mortality (aOR 14.93; 95% CI 1.32-168.26; p = 0.029). Third-generation cephalosporin-based definitive regimens were associated with reduced mortality (aOR 0.10; 95% CI 0.01-0.81; p = 0.032).
conclusionMost deaths occurred early and were associated with disease severity. Reduced susceptibility to penicillin and ceftriaxone was observed. Septic shock predicted mortality, whereas third-generation cephalosporin-based definitive therapy was associated with improved survival. Early recognition and appropriate antimicrobial therapy remain essential.
Indexed as
Identifiers
42295645What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.