Evidence map›Paper›PMID 42295576›Full record

ReviewApplied biochemistry and biotechnology2026

Dye-Decolorizing Peroxidase for Lignin Depolymerization: a Comprehensive Review on Enzyme Structural Characteristics, Reaction-Influencing Factors and Efficiency-Enhancing Strategies.

Yuheng Xie, Shufan Zhao, Feng Guo, Yujia Jiang, Wenming Zhang, Fengxue Xin, Wankui Jiang, Min Jiang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuheng XieState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.
Shufan ZhaoState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.
Feng GuoState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.
Yujia JiangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.
Wenming ZhangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.
Fengxue XinState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China. xinfengxue@njtech.edu.cn.
Wankui JiangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China. jiangwankui@njtech.edu.cn.
Min JiangState Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Puzhu South Road 30#, Nanjing, 211800, People's Republic of China.

Funding

Jiangsu Agriculture Science and Technology Independent Innovation Fund Project CX(24) 3085Jiangsu Agriculture Science and Technology Independent Innovation Fund Project JASTIFNational Key Research and Development Program of China 2023YFC3403500Shandong Province Science and Technology based Small and Medium sized Enterprises Innovation Capability Enhancement Project 2025TSGCCZZB0588State Key Laboratory of Materials-Oriented Chemical Engineering KL-MCE-23A10the National Natural Science Foundation of China 22378199the National Natural Science Foundation of China 22408164the National Natural Science Foundation of China 22478183Young Elite Scientists Sponsorship Program by Jiangsu JSTJ-2025-616
6 · The paper itself

Abstract

As a renewable material in nature, lignin holds great potentials as a renewable alternative to replace fossil fuels. Its unique aromatic structure and properties have attracted extensive research attentions. Compared with traditional methods for lignin depolymerization, the biological depolymerization of lignin was not only carried out under mild reaction conditions with low energy consumption, but also offers advantages such as reduced pollution et al. As a member of the peroxidase family, dye-decolorizing peroxidase (DyP) exhibits excellent lignin depolymerization capabilities, providing new insights into the bioenzymatic lignin depolymerization. There have been reports on the use of DyPs in lignin depolymerization. However, there is currently a lack of review on the application of DyP in lignin depolymerization. This review summarized the properties of various lignin and DyP followed by an overview of depolymerization reactions and their influencing factors, systematically analyzing the effects of these factors on the reactions and evaluating current strategies for improving depolymerization efficiency. Finally, based on protein engineering and other technologies, feasible solutions to enhance the efficiency of depolymerization reactions were also proposed, aiming to promote better application of DyP in lignin depolymerization.

Indexed as

Coloring AgentsLigninPeroxidasePeroxidasesPolymerizationColoring AgentsLigninPeroxidasePeroxidasesDepolymerizationDye-decolorizing peroxidaseLigninValorization

Identifiers

PMID42295576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.