Evidence map›Paper›PMID 42295525›Full record

ArticleObesity surgery2026

An Investigation of Elevated Serum Copper Levels Following Bariatric Surgery.

Katherine McKeon, Michael Cook, John Baker, Kyle LaPenna, Jake Doiron, Arti Shankar, Erica Felker-Kantor, Felicia Rabito

Abstract read
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In one paragraph

Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katherine McKeonTulane University, New Orleans, LA, USA. kmckeon2@tulane.edu.
Michael CookLouisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
John BakerTulane University, New Orleans, LA, USA.
Kyle LaPennaLouisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Jake DoironLouisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Arti ShankarTulane University, New Orleans, LA, USA.
Erica Felker-KantorTulane University, New Orleans, LA, USA.
Felicia RabitoTulane University, New Orleans, LA, USA. rabito@tulane.edu.

Funding

Deep South KUH Premier Research - Interdisciplinary Mentored Education (PRIME) Training CoreTL1DK139566 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID M POLLOCK · 2023 to 2026
$3.6M
Tulane University Training Program for Diversity in tRanslation and Implementation research in cardioVascular disEase (DRIVE)T32HL158290 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI MACLEHOSE, RICHARD F · 2021 to 2025
$933k
NHLBI NIH HHS T32 HL158290NIDDK NIH HHS TL1 DK139566
6 · The paper itself

Abstract

backgroundBariatric surgery alters physiology and dietary absorption, which may influence trace metal homeostasis. Copper (Cu), an essential micronutrient linked to inflammation and obesity and has been found to be elevated in a pre-surgery bariatric patient population. This study followed the cohort and evaluated changes in serum Cu after bariatric surgery and identified demographic, metabolic, and biochemical factors associated with elevated post-surgery Cu.

methodsWe performed a retrospective cohort study involving electronic health record (EHR) data from 523 bariatric surgery patients at University Medical Center-New Orleans (2018-2024). The analysis included preoperative and 12- to 24-month postoperative Cu measurements and covariates related to Cu metabolism. Serum Cu levels were analyzed as continuous variables and categorized as elevated (≥ 140 mcg/dl). Quantile and logistic regression models were utilized.

resultsParticipants were predominantly female (93.8%) and Black (69.2%), with a median age of 40.9 years. The median Cu level decreased from 142.1 mcg/d pre-surgery to 128.0 mcg/dl post-surgery; however, 30.8% of participants continued to have levels ≥ 140 mcg/dl. In adjusted models, higher post-surgical Cu levels were associated with pre-surgical Cu (p < 0.001), body mass index (BMI) (p = 0.003), zinc ( p = 0.002), and Black race (p = 0.005). Black patients were 2.37 more likely to have elevated post-surgical Cu compared to White patients. DISCUSSION: Elevated Cu levels persisted in approximately one-third of patients up to two years following surgery, with a higher prevalence observed among Black individuals. Additional research on factors associated with elevated Cu and racial differences are needed.

Indexed as

Bariatric SurgeryCopperObesity, MorbidAdultBody Mass IndexFemaleHumansMaleMiddle AgedPostoperative PeriodRetrospective StudiesCopper

Identifiers

PMID42295525

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.