ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
A dyadic approach to understanding anxiety and child overall health in pediatric oncology: insights from an actor-partner interdependence model.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThough child and caregiver anxiety are known to contribute to child overall health, this has not been examined dyadically. This cross-sectional study dyadically examined anxiety (child-self, caregiver-self) and child overall health (child-self, caregiver-proxy) in pediatric cancer.
methodsChildren and caregivers (n = 76 dyads; n = 152) from two Midwestern children's hospitals self- or proxy-reported child overall health, and their own anxiety. Descriptive statistics and bivariate analyses (e.g., correlations, t-tests) examined associations among demographics, medical characteristics, and focal variables. An Actor-Partner Interdependence Model (APIM) evaluated dyadic associations between child and caregiver self-reports of anxiety (independent variables) and child self- and caregiver proxy-reports of child overall health (dependent variables). Associations between independent and dependent variables for one reporter are actor effects, whereas across reporters are partner effects.
resultsAmong 76 child (88.2% White; 34.2% Female; M = 13.35-years-old, SD = 3.20) and caregiver (92.1% White, 69.7% Female) dyads, children (M = 46.64, SD = 9.09) and caregivers (M = 39.33, SD = 8.97) reported below-average child overall health. Children reported below-average anxiety levels (M = 46.31, SD = 10.05), and caregivers reported above-average anxiety levels (M = 55.18, SD = 8.37). APIM analyses revealed significant actor effects: higher levels of self-reported anxiety were associated with lower levels of child overall health (b = - 0.29, p < .001). Marginally non-significant partner effects revealed greater anxiety was linked to lower partner reports of child overall health (b = - 0.14, p = 0.051).
conclusionOur findings underscore supporting the family system within pediatric cancer and suggest mitigating caregiver anxiety may have downstream benefits. Interventions are needed for caregivers and children to support their mental and overall health during cancer treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.