Evidence map›Paper›PMID 42295425›Full record

ArticlePediatric surgery international2026

Do pediatric patients with cerebral palsy have worse outcomes after anti-reflux esophageal surgery?

Sasabong Tiyaamornwong, Kulpreeya Sirichamratsakul, Piyawan Chiengkriwate, Atchariya Chanpong, Surasak Sangkhathat

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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Sasabong TiyaamornwongPediatric Surgery Unit, Division of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Kulpreeya SirichamratsakulPediatric Surgery Unit, Division of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Piyawan ChiengkriwatePediatric Surgery Unit, Division of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Atchariya ChanpongDepartment of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, 90110, Songkhla, Thailand.
Surasak SangkhathatDivision of Pediatric Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand. surasak.sag@mahidol.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate and compare short-term and two-year outcomes, particularly aspiration pneumonia-free survival, after fundoplication in pediatric patients with and without cerebral palsy (CP).

methodThe study reviewed outcomes after fundoplication in pediatric patients performed between 2004 and 2025 at a university hospital in Thailand, focusing on aspiration pneumonia-free survival. Statistical analyses used log-rank test and Cox proportional hazards model.

resultsDuring the study, 85 cases underwent surgery. Diagnoses included gastroesophageal reflux (84.7%) and hiatal hernia (10.9%). Forty-five cases (52.9%) had CP, with significantly higher rates of co-occurring epilepsy (OR 33.9) and recurrent pneumonia (OR 3.6). Post-procedure, first-year pneumonia episodes were similar (median 0 occurrence in the CP group and 0.5 occurrence in the non-CP, p = 0.473). The mean interval to first pneumonia was longer in CP (418 days) than in non-CP (209 days, p = 0.049). One-year overall survival was 69.6%. One-year pneumonia-free survival in CP (50.4%) did not differ from non-CP (51.5%, p = 0.29).

conclusionDespite a higher comorbidity burden and nutritional support needs, fundoplication outcomes in pediatric patients with CP were comparable to those without CP. These findings suggest fundoplication is an equally effective and safe surgical option for anti-reflux management in pediatric patients with CP.

Indexed as

Cerebral PalsyFundoplicationGastroesophageal RefluxAdolescentChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMalePneumonia, AspirationPostoperative ComplicationsRetrospective StudiesThailandTreatment OutcomeAspiration pneumoniaCerebral palsyFundoplicationGastroesophageal refluxRecurrent pneumonia

Identifiers

PMID42295425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.