Evidence map›Paper›PMID 42295341›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Older age and post-traumatic organ failure a TraumaRegister DGU

Tim Niklas Bewersdorf, Rolf Lefering, Stephan Stein, Jan Streblow, Sebastian Findeisen, Gerhard Schmidmaier, Tobias Grossner

Abstract read
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In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tim Niklas BewersdorfFaculty of Medicine, Heidelberg University, 69120, Heidelberg, Germany. timniklas.bewersdorf@med.uni-heidelberg.de.ORCID http://orcid.org/0000-0002-1188-4791
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), University of Witten / Herdecke, Cologne, Germany.ORCID http://orcid.org/0000-0002-0141-1747
Stephan SteinHeidelberg Trauma Research Group, Clinic for Trauma and Reconstructive Surgery, Centre for Orthopaedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, 69120, Heidelberg, Germany.ORCID http://orcid.org/0009-0002-3563-0283
Jan StreblowHeidelberg Trauma Research Group, Clinic for Trauma and Reconstructive Surgery, Centre for Orthopaedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, 69120, Heidelberg, Germany.ORCID http://orcid.org/0009-0006-8903-1621
Sebastian FindeisenHeidelberg Trauma Research Group, Clinic for Trauma and Reconstructive Surgery, Centre for Orthopaedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-4083-1311
Gerhard SchmidmaierHeidelberg Trauma Research Group, Clinic for Trauma and Reconstructive Surgery, Centre for Orthopaedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6711-7380
Tobias GrossnerHeidelberg Trauma Research Group, Clinic for Trauma and Reconstructive Surgery, Centre for Orthopaedics, Trauma Surgery and Spinal Cord Injury, University Hospital Heidelberg, 69120, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-8953-9384

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs the number of elderly major trauma patients (EMTP) increases continuously, this study sought to determine the incidence of organ failure (OF) and multiple organ failure (MOF) and their impact on mortality and recovery status in this cohort.

methodsBased on the German TraumaRegister DGU

resultsThe database revealed 34,469 EMTP, here 37% suffered from OF (16.0%) or MOF (21.0%). Mortality was significantly higher in OF and MOF patients compared to non-OF patients (non-OF: 7.4%; OF: 45.0%; MOF: 59.0%; p < 0.001). 80.9% of all deaths were associated with failure of at least one organ and 51.1% of non-survivors suffered from MOF. Highest odds ratios (OR) for mortality were found for liver (OR: 5.13, p < 0.001), central nervous system (OR: 3.63, p < 0.001) and renal failure (OR: 3.25, p < 0.001), followed by cardiovascular (OR: 1.95, p < 0.001) and lung failure (OR: 1.16, p = 0.010). Haemostatic failure had no impact on mortality.

conclusionOR and mortality differ significantly between distinct OFs due to varying degrees of success in treatment options and systemic impact of these OFs. Clinicians should be aware that OF and MOF occur frequently in EMTP and that these patients have a high risk of dying. Therefore, close screening for and prompt treatment of OF and MOF could be a key strategy to lower mortality of EMTP.

Indexed as

Multiple Organ FailureMultiple TraumaWounds and InjuriesAgedAged, 80 and overAge FactorsFemaleGermanyHumansIncidenceInjury Severity ScoreMaleOrgan Dysfunction ScoresRegistriesRisk FactorsElderly major trauma patientsMortality risk factorsPost-traumatic multiple organ failurePost-traumatic organ failureTraumaRegister DGU®

Identifiers

PMID42295341
PMCPMC13269517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.