Evidence map›Paper›PMID 42295281›Full record

ArticleJournal of personality and social psychology2026

Is my loneliness killing me? Effects of loneliness and social isolation on transitions between cognitive status categories and death.

Tomiko Yoneda, Kathryn L Jackson, Emily C Noyer, Christopher R Beam, Gabrielle Pfund, Stephen Antonoplis, Emorie Beck, Katy Bedjeti, Pei Qin, Kayla M Garner and 14 more

Abstract read
In one paragraph

Article in Journal of personality and social psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Tomiko YonedaDepartment of Psychology, University of California, Davis.ORCID 0000-0002-2906-1881
Kathryn L JacksonDepartment of Medical Social Sciences, Northwestern University.
Emily C NoyerDepartment of Psychology, University of California, Davis.
Christopher R BeamDepartment of Psychology, University of Southern California.
Gabrielle PfundDepartment of Human Development and Family Science, Auburn University.
Stephen AntonoplisDepartment of Psychology, University of California, Riverside.
Emorie BeckDepartment of Psychology, University of California, Davis.ORCID 0000-0002-8152-3510
Katy BedjetiDepartment of Medical Social Sciences, Northwestern University.
Pei QinDepartment of Behavioural Sciences and Health, University College London.
Kayla M GarnerDepartment of Psychology, Northwestern University.
Jing LuoDepartment of Medical Social Sciences, Northwestern University.
Karina Van BogartDepartment of Medical Social Sciences, Northwestern University.ORCID 0000-0002-1473-3112
Lily PieramiciDepartment of Psychology, Northwestern University.
Katherina HaunerDepartment of Medical Social Sciences, Northwestern University.
Nicholas A TurianoDepartment of Psychology, West Virginia University.ORCID 0000-0002-2266-2959
Páraic S O'SúilleabháinDepartment of Psychology, University of Limerick.
Lisa BarnesRush Alzheimer's Disease Center, Rush University Medical Center.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center.
Graciela Muniz TerreraDepartment of Social Medicine, Heritage College of Osteopathic Medicine, Ohio University.
Daniel K MroczekDepartment of Medical Social Sciences, Northwestern University.
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center.
Andrew SteptoeDepartment of Behavioural Sciences and Health, University College London.
Anthony D OngDepartment of Psychology, Cornell University.
Eileen K GrahamDepartment of Medical Social Sciences, Northwestern University.

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Capturing social and cognitive health dynamics as digital risk biomarkers of Alzheimer's diseaseRF1AG088206 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BECK, EMORIE DANIELLE · 2025 to 2025
$3.4M
Personality prediction of dementia risk and progressionR01AG067622 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MROCZEK, DANIEL K. · 2019 to 2023
$3.2M
Consortium for Longitudinal behavioral and Social Science data Integration and Coordination (CLASSIC)U24AG081810 · NIA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SHEVAUN D NEUPERT, Stacey Beth Scott · 2025 to 2026
$3.2M
Advancing the Study of Personality, Interpersonal Stress, and Cognitive Aging Through The Use of Integrative Data AnalysisRF1AG094591 · NIA · NORTHWESTERN UNIVERSITY · PI GRAHAM, EILEEN KRANZ, LUO, JING · 2025 to 2025
$3.1M
Advancing the Study of Social Isolation, Loneliness, and Cognitive Functioning in Older Adults Through the Use of Integrative Data AnalysisR01AG082954 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Eileen Kranz Graham · 2023 to 2026
$2.4M
Personality Prediction of Dementia Risk and ProgressionRF1AG067622 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MROCZEK, DANIEL K. · 2024 to 2024
$2.3M
NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG067622NIA NIH HHS R01 AG082954NIA NIH HHS RF1 AG067622NIA NIH HHS RF1 AG088206NIA NIH HHS RF1 AG094591NIA NIH HHS U24 AG081810NIH HHS
6 · The paper itself

Abstract

Loneliness and social isolation are associated with numerous adverse physical and psychological health outcomes in older adulthood, including cognitive impairment and mortality risk. Yet, how the individual and joint effects of loneliness and social isolation contribute to these outcomes remains unclear, particularly given the interplay between individual differences (loneliness) and environmental factors (social isolation) in shaping these important health outcomes in older adulthood (i.e., person-environment interactions). We used Cox regression, logistic regression, and multistate survival models to systematically investigate the individual and adjusted associations among loneliness, social isolation, cognitive aging outcomes, and mortality risk. Further, extensive between-study variability in operational definitions, modeling approaches, and covariate adjustments may be contributing to mixed results in the existing literature. In this registered report, we applied a multistudy approach (i.e., coordinated data analysis) in which independent but identical models were fit across 11 longitudinal studies representing participants from 18 countries (

Indexed as

Cognitive AgingCognitive DysfunctionDeathLonelinessSocial IsolationAgedFemaleHumansLongitudinal StudiesMale

Identifiers

PMID42295281
PMCPMC13271175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.