Evidence map›Paper›PMID 42294773›Full record

ArticlePalliative & supportive care2026

Substance use risk and controlled substances discussions in cancer care: Observations from audio-recorded patient-clinician encounters.

Miryam Yusufov, Kathryn I Pollak, Hanneke Poort, Yvan Beaussant, Elise C Tarbi, Richard E Leiter, James A Tulsky

Abstract read
In one paragraph

Article in Palliative & supportive care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miryam YusufovDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.ORCID https://orcid.org/0000-0002-0254-3864
Kathryn I PollakCancer Prevention and Control, Duke Cancer Institute, Durham, North Carolina, USA.
Hanneke PoortDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.
Yvan BeaussantDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.ORCID https://orcid.org/0000-0003-3716-6736
Elise C TarbiDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.
Richard E LeiterDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.
James A TulskyDepartment of Supportive Oncology, Dana-Farber Cancer Institutehttps://ror.org/02jzgtq86, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients with advanced cancer frequently experience pain and psychological distress, often requiring controlled substances such as opioids and benzodiazepines. Although access to these medications increases risk of substance misuse, little is known about how clinicians and patients discuss controlled substance use during cancer care. Understanding these conversations may inform safer prescribing, improve patient outcomes, and support management of substance use disorder (SUD) risk. We aimed to characterize discussions of controlled substance use in oncology visits, including who initiated conversations, clinician responses, and verbalized SUD risk factors.

methodsFive coders reviewed 826 audio-recorded oncology visits from a prior clinical trial. Encounters were coded for substance type, initiator (patient, clinician, both, neither), clinician/patient response style (avoidant, concerned/emotional, engaged, neutral, resistant), and substance misuse risk factors.

resultsMean patient age was 59.5 years; most were female (55.8%), White (81.7%), and married (71.7%). Substance-related content appeared in 14.6% of counters ( SIGNIFICANCE OF

resultsDespite widespread prescribing of controlled substances in oncology, discussions remain infrequent, and clinician responses to SUD-related concerns are often insufficient. These findings highlight opportunities to improve communication and risk management in cancer care.

Indexed as

Controlled SubstancesNeoplasmsPhysician-Patient RelationsSubstance-Related DisordersAdultAgedAnalgesics, OpioidBenzodiazepinesFemaleHumansMaleMiddle AgedRisk FactorsTape RecordingAnalgesics, OpioidBenzodiazepinesControlled SubstancesBehavioral medicinecancer carecontrolled substancespainstigmasubstance use

Identifiers

PMID42294773
PMCPMC13280578

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.