Evidence map›Paper›PMID 42294722›Full record

ArticleMicrobiology spectrum2026

Multiple cross displacement amplification coupled with a lateral flow biosensor for ultra-rapid and highly sensitive detection of

Ruoyi Xiao, Peicen Zou, Juan Zhou, Ying Li, Ying Chen, Pan Huang, Yi Wang, Yajuan Wang

Abstract readEvaluation Study
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruoyi Xiao *Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Peicen Zou *Capital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0001-7407-3227
Juan ZhouExperimental Research Center, Capital Center for Children's Health, Capital Medical University, Beijing, China.ORCID 0000-0002-3168-7111
Ying LiDepartment of Neonatology, Capital Center for Children's Health, Capital Medical University, Beijing, China.
Ying ChenDepartment of Neonatology, Capital Center for Children's Health, Capital Medical University, Beijing, China.
Pan HuangDepartment of Neonatology, Capital Center for Children's Health, Capital Medical University, Beijing, China.
Yi WangExperimental Research Center, Capital Center for Children's Health, Capital Medical University, Beijing, China.ORCID 0000-0002-2031-087X
Yajuan WangCapital Institute of Pediatrics, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.ORCID 0000-0002-8830-7255

Funding

Beijing Natural Science Foundation 7232009Beijing Nova Programme Interdisciplinary Cooperation Project, the National Natural Science Foundation of China 82574169High-level Public Health Technical Personnel Construction Project of Beijing Municipal Health Commission High-level Public Health Technical Personnel Construction Project of Beijing Municipal Health Commission
6 · The paper itself

Abstract

IMPORTANCE: Neonatal sepsis requires rapid and accurate pathogen identification to support timely antimicrobial therapy, yet conventional blood culture is often slow and has limited sensitivity, particularly in neonates with small sample volume or prior antibiotic exposure. In this study, we developed a visual multiple cross displacement amplification-lateral flow biosensor (MCDA-LFB) assay for rapid detection of

Indexed as

Biosensing TechniquesEscherichia coliEscherichia coli InfectionsNeonatal SepsisNucleic Acid Amplification TechniquesDNA, BacterialEscherichia coli ProteinsHumansInfant, NewbornRapid Diagnostic TestsSensitivity and SpecificityDNA, BacterialEscherichia coli ProteinsEscherichia colilateral flow biosensormultiple cross displacement amplificationneonatal sepsisrapid detection

Identifiers

PMID42294722
PMCPMC13340188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.