Evidence map›Paper›PMID 42294629›Full record

ArticleJournal of virology2026

The nicotinamide phosphoribosyltransferase inhibitor FK866 restricts influenza A virus replication by perturbing viral polymerase activity.

Changjie Lv, Shuang Wang, Mingyue Song, Jianmei Wu, Wanxin Wei, Guijie Guo

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changjie Lv *Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.ORCID 0000-0002-1774-5063
Shuang Wang *Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Mingyue SongKey Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Jianmei WuJoint Laboratory of Animal Pathogen Prevention and Control of Fujian-Nepal, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Wanxin WeiKey Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Guijie GuoKey Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.ORCID 0000-0002-9031-1915

Funding

National Natural Science Foundation of China 32372998National Natural Science Foundation of China 32402928National Natural Science Foundation of China U25A20713
6 · The paper itself

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT), a key rate-limiting enzyme in NAD

Indexed as

AcrylamidesAntiviral AgentsInfluenza A virusNicotinamide PhosphoribosyltransferasePiperidinesRNA-Dependent RNA PolymeraseViral ProteinsVirus ReplicationAnimalsCytokinesDogsEnzyme InhibitorsHumansMadin Darby Canine Kidney CellsMiceOrthomyxoviridae InfectionsAcrylamidesAntiviral AgentsCytokinesEnzyme Inhibitorsinfluenza virus polymerase basic protein 1N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamideNicotinamide PhosphoribosyltransferasePiperidinesRNA-Dependent RNA PolymeraseViral ProteinsFK866influenza A virusNAMPTPB1virus replication

Identifiers

PMID42294629
PMCPMC13386833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.