Evidence map›Paper›PMID 42294567›Full record

SynthesisTropical medicine & international health : TM & IH2026

Beyond the Mosquito: Social Determinants of Health and Global Strategies for Aedes-Borne Disease Control.

Hakimeh Mostafavi, Jawad Jafarzadeh, Efat Mohamadi, Fatemeh Mohamadi, Ghobad Moradi, Maryam Sargolzaei Moghaddam, Fateme Yaftian, Amin Ghanbarnejad, Mehrnaz Mozafari, Enayatollah Homaie Rad and 5 more

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in Tropical medicine & international health : TM & IH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hakimeh MostafaviHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.ORCID https://orcid.org/0000-0002-1969-7341
Jawad JafarzadehHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.ORCID https://orcid.org/0009-0005-0947-3271
Efat MohamadiHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Fatemeh MohamadiHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Ghobad MoradiSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.ORCID https://orcid.org/0000-0003-2612-6528
Maryam Sargolzaei MoghaddamIranian Center for Communicable Disease Control (CDC), Ministry of Health & Medical Education, Tehran, Iran.
Fateme YaftianHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Amin GhanbarnejadIranian Research Network for Social Determinants of Health (IRNSDH), Tehran, Iran.
Mehrnaz MozafariBushehr University of Medical Sciences, Bushehr, Iran.
Enayatollah Homaie RadIranian Research Network for Social Determinants of Health (IRNSDH), Tehran, Iran.ORCID https://orcid.org/0000-0002-9064-0380
Ehsan Sheykh NooriDepartment of Disease Prevention and Control, Chabahar University of Medical Sciences, Chabahar, Iran.
Marziyeh NajafiTDR Grantee at IIHMR, Jaipur, India.
Amirhossein TakianHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Ahad BakhtiariHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.ORCID https://orcid.org/0000-0003-3580-9259
Alireza OlyaeemaneshHealth Equity Research Center (HERC), Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAedes-borne diseases, including dengue, chikungunya and Zika, have emerged as a growing global health concern, particularly in tropical and subtropical regions. Their spread is not only driven by biological and environmental factors but also shaped by a wide range of social determinants of health (SDH). This systematic review synthesizes available evidence on SDH that shape the transmission, prevention and control of these diseases, as well as the strategies implemented internationally to address them.

methodsWe conducted five systematic reviews following PRISMA guidelines, each corresponding to one of the major Aedes-borne diseases (dengue, chikungunya, Zika and other Aedes-related illnesses). Searches were performed in PubMed and Scopus for the period 2000-2024, using both MeSH terms and free-text keywords. Quality appraisal was conducted using appropriate checklists, that is, CASP, STROBE and results were synthesized narratively. Thematic coding was applied to identify patterns across social, economic and environmental determinants, while intervention data were summarized descriptively.

resultsThe systematic search figured out a large number of potentially relevant records across the five reviews. One hundred sixty-nine studies were included for full analysis including 27 studies on Aedes in general, 54 on dengue, 3 on chikungunya, 14 on Zika and 71 on preventive interventions. The main themes that emerged from the study analysis included: Poverty and Related Indicators, Education and Health Literacy, Community Engagement, Urban Infrastructure and Social Support, Access to Health Services, Demographic Factors, Culture and Beliefs and Migration and Human Mobility. Interventions that engaged communities and combined educational, infrastructural and environmental actions demonstrated the greatest impact and sustainability. DISCUSSION: Findings of the study suggest that effective and sustainable Aedes-borne disease control depends on tackling structural inequities-particularly poverty and poor urban infrastructure-while promoting health literacy and community engagement. Future research should further investigate underexplored determinants, including cultural and migratory factors, to inform context-specific, multisectoral responses.

Indexed as

AedesChikungunya FeverDengueMosquito ControlSocial Determinants of HealthZika Virus InfectionAnimalsGlobal HealthHumansMosquito-Borne DiseasesMosquito VectorsSocioeconomic Factorsaedes‐borne diseasecontrolglobal strategiessocial determinants of health

Identifiers

PMID42294567
PMCPMC13533637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.