Evidence map›Paper›PMID 42294475›Full record

ArticleCase reports in oncology

Delayed Postoperative Wound Healing during Alectinib Therapy for Poorly Differentiated Lung Adenocarcinoma: A Case Report.

Yanhua He, Gongdan Xu, Xue Yang, Lu Li, Mingying Tan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanhua HeOutpatient Department, West China Hospital, Sichuan University, Chengdu, PR China.
Gongdan XuOutpatient Department, West China Tianfu Hospital, Sichuan University, Chengdu, PR China.
Xue YangGeriatrics, West China Hospital, Sichuan University, Chengdu, PR China.
Lu LiOutpatient Department, West China Hospital, Sichuan University, Chengdu, PR China.
Mingying TanOutpatient Department, West China Hospital, Sichuan University, Chengdu, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Anaplastic lymphoma kinase (ALK) rearrangement is a key oncogenic driver in non-small cell lung cancer. Alectinib, a highly selective second-generation ALK inhibitor, has demonstrated remarkable clinical efficacy; however, its potential influence on postoperative wound healing remains unclear. Case Presentation: We report the case of a 42-year-old male with ALK-positive poorly differentiated lung adenocarcinoma who underwent right lower lobectomy following significant tumor regression with alectinib therapy. Postoperatively, the patient developed delayed wound healing complicated by Conclusion: This case highlights the possibility that alectinib may impair postoperative wound repair. Comprehensive perioperative drug evaluation, multidisciplinary collaboration, and carefully monitored treatment interruption are recommended to maintain the balance between oncologic control and effective tissue healing.

Indexed as

Adverse reactionAlectinibAnaplastic lymphoma kinase-positive lung cancerDelayed wound healingPoorly differentiated lung adenocarcinoma

Identifiers

PMID42294475
PMCPMC13263002

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.