Evidence map›Paper›PMID 42294464›Full record

ArticleVirus evolution2026

Extreme GC3 codon bias in a novel brown seaweed virus results in pseudoambigrammatic characteristics.

Rob J Dekker, Wim C de Leeuw, Han Rauwerda, Marina F van Olst, Wim A Ensink, Selina M van Leeuwen, Job Cohen, Klaas Timmermans, Timo M Breit, Martijs J Jonker

Abstract read
In one paragraph

Article in Virus evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rob J DekkerRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-2662-8715
Wim C de LeeuwRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Han RauwerdaRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Marina F van OlstRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Wim A EnsinkRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Selina M van LeeuwenRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Job CohenNIOZ Royal Netherlands Institute for Sea Research, Department of Estuarine and Delta Systems, Korringaweg 7, 4401 NT Yerseke, The Netherlands.
Klaas TimmermansNIOZ Royal Netherlands Institute for Sea Research, Department of Estuarine and Delta Systems, Korringaweg 7, 4401 NT Yerseke, The Netherlands.
Timo M BreitRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.
Martijs J JonkerRNA Biology Research Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although viruses are often studied in relation to disease, they can also offer valuable insights into RNA functionality. Due to their vast range of hosts and high mutation rates, viruses can quickly adapt to changing environments. It is therefore likely that viruses exploit a broad range of RNA functionalities to develop strategies for host infection and propagation. Our aim is to discover RNA viruses with survival strategies that reveal unknown RNA characteristics and functionalities. Here, we report a new, unclassified negative-sense single-stranded RNA virus from the large brown seaweed

Indexed as

GC3 codon biasNegarnaviricotanegative-sense single-stranded RNA virus (–ssRNA)pseudoambigrammatic virusSaccharina latissimaRNA-dependent RNA polymerase (RdRp)

Identifiers

PMID42294464
PMCPMC13262655

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.