Evidence map›Paper›PMID 42294185›Full record

ArticleACS omega2026

Urinary Iodine Quantification in Epidemiological Studies: Optimization in Sample Preparation of the Sandell-Kolthoff Method.

Daniel Rosenkranz, David Vennen, Antje Kneuer, Gunnar Brandhorst, Nele Friedrich, Till Ittermann, Henry Völzke, Matthias Nauck, Martin Schlaud, Astrid Petersmann

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel RosenkranzUniversity Institute for Clinical Chemistry and Laboratory Medicine, Oldenburg 26133, Germany.ORCID https://orcid.org/0009-0001-2037-6027
David VennenUniversity Institute for Clinical Chemistry and Laboratory Medicine, Oldenburg 26133, Germany.
Antje KneuerDepartment for Epidemiology and Health Monitoring, Robert Koch Institute, Berlin 13353, Germany.
Gunnar BrandhorstUniversity Institute for Clinical Chemistry and Laboratory Medicine, Oldenburg 26133, Germany.
Nele FriedrichUniversity Institute for Clinical Chemistry and Laboratory Medicine, Greifswald 17475, Germany.
Till IttermannInstitute for Community Medicine, University Medicine Greifswald, Greifswald 17489,Germany.
Henry VölzkeGerman Centre for Cardiovascular Research, Partner Site, Greifswald 17475,Germany.
Matthias NauckUniversity Institute for Clinical Chemistry and Laboratory Medicine, Greifswald 17475, Germany.
Martin SchlaudDepartment for Epidemiology and Health Monitoring, Robert Koch Institute, Berlin 13353, Germany.
Astrid PetersmannUniversity Institute for Clinical Chemistry and Laboratory Medicine, Oldenburg 26133, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present an optimized Sandell-Kolthoff (SK) spectrophotometric method for urinary iodine quantification, developed to enhance analytical accuracy, robustness, and suitability for high-throughput applications while minimizing reagent consumption. A stepwise refinement of an established protocol (Mod 1-4) was performed by adjusting reagent volumes, digestion temperature, and reaction conditions. The final optimized method (Mod 4) demonstrated excellent calibration linearity (

Identifiers

PMID42294185
PMCPMC13261426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.