Ecthyma gangrenosum in a patient with metastatic leiomyosarcoma undergoing chemotherapy: a case report.

Grace Getman, Taryn Boucher, Vicki Keedy, Melinda New, Alison Barlow, Lauren Prescott

Abstract readCase Reports

In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Grace GetmanVanderbilt University School of Medicine, 1161 21 Ave S, #D3300, Nashville, TN 37232, USA.

Taryn BoucherDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA.

Vicki KeedyDivision of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA.

Melinda NewDepartment of Obstetrics and Gynecology, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA.

Alison BarlowDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA.

Lauren PrescottDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ecthyma gangrenosum (EG) is a rare necrotizing skin infection most commonly associated with Case presentation: A 40 year-old patient with metastatic leiomyosarcoma presented two-weeks after initiating chemotherapy with multiple necrotic vulvar lesions with an erythematous rim, characteristic of EG. She had no systemic symptoms. She was treated empirically with ciprofloxacin and wound cultures confirmed Conclusion: This represents the second reported case of EG in a patient with gynecologic malignancy. It highlights that EG may present without systemic symptoms, even in high-risk neutropenic patients, and underscores the importance of early detection and antipseudomonal antibiotic initiation to prevent adverse outcomes associated with EG in vulnerable oncologic populations.

Indexed as

Antipseudomonal antibioticsCase reportEcthymagangrenosumLeiomyosarcomaPancytopeniaVulvar lesions

Identifiers

PMID42294117

DOI10.1016/j.gore.2026.102129

PMCPMC13264180

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