Evidence map›Paper›PMID 42294026›Full record

ArticleACS polymers Au2026

Designing Water-Soluble Macromolecules for Biomedical Use: PEG Chains versus Amino AcidsA Case Study in MRI Contrast Agents.

Yufei Wu, Carlos Caro, Esther Matamoros, Jesús David Urbano-Gámez, Silvia Lope-Piedrafita, Yolanda Vida, María Luisa García-Martín, José Vidal-Gancedo, Vega Lloveras

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS polymers Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yufei WuInstitut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.
Carlos CaroBiomedical Magnetic Resonance Laboratory-BMRL, Andalusian Public Foundation Progress and Health-FPS, Avda. Américo Vespucio, 15, 41092 Seville, Spain.
Esther MatamorosDepartamento de Química Orgánica,Universidad de Málaga, 29071 Málaga, Spain.
Jesús David Urbano-GámezBiomedical Magnetic Resonance Laboratory-BMRL, Andalusian Public Foundation Progress and Health-FPS, Avda. Américo Vespucio, 15, 41092 Seville, Spain.
Silvia Lope-PiedrafitaDepartament de Bioquímica i Biologia Molecular, Unitat de Biofísica, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.ORCID https://orcid.org/0000-0002-8127-6425
Yolanda VidaDepartamento de Química Orgánica,Universidad de Málaga, 29071 Málaga, Spain.ORCID https://orcid.org/0000-0002-7004-4629
María Luisa García-MartínBiomedical Magnetic Resonance Laboratory-BMRL, Andalusian Public Foundation Progress and Health-FPS, Avda. Américo Vespucio, 15, 41092 Seville, Spain.ORCID https://orcid.org/0000-0002-2257-7682
José Vidal-GancedoInstitut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.ORCID https://orcid.org/0000-0002-1853-9675
Vega LloverasInstitut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Spain.ORCID https://orcid.org/0000-0002-9653-3340

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding how macromolecular architecture and interfacial hydration govern magnetic relaxation is crucial for the rational design of next-generation Magnetic Resonance Imaging (MRI) contrast agents. Here, we compare two water-solubilization strategies for organic radical dendrimers: using short-chain poly-(ethylene glycol) (PEG) linkers versus amino acid-derived carboxylate sodium salt linkers. By synthesizing third- and fourth-generation dendrimers functionalized with these respective groups (denoted as GnPEG and GnNa, where

Indexed as

biomaterialsdynamic contrast-enhanced MRImolecular dynamicsMRI contrast agentsradical dendrimersrelaxivitywater-soluble

Identifiers

PMID42294026
PMCPMC13261739

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.