Evidence map›Paper›PMID 42293857›Full record

ArticleTranslational andrology and urology2026

Correlation between reproductive hormone levels and genetic abnormalities in patients with non-obstructive azoospermia and oligospermia.

Yuhe Fu, Liang Hu, Jinxing Liu, Yuanyuan Pei, Xiaojin Luo, Jiangtao Bai, Weiqiang Liu

Abstract read
In one paragraph

Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuhe Fu *Department of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Liang Hu *Department of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Jinxing LiuDepartment of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Yuanyuan PeiDepartment of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Xiaojin LuoDepartment of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Jiangtao BaiDepartment of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.
Weiqiang LiuDepartment of Central Laboratory (Genetics lab), Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although male infertility has been studied extensively, the relationship between genetic abnormalities and reproductive hormone levels remains to be explored. This study investigates the causes of non-obstructive azoospermia and oligospermia, focusing on their association with sperm concentration, reproductive hormone levels, and genetic factors. Methods: We retrospectively analyzed data from 144 male infertility patients, examining karyotyping, the azoospermia factor ( Results: Our analysis revealed significant differences in reproductive hormone levels between the azoospermia, severe oligospermic, and healthy control groups (P<0.05). Specifically, prolactin (PRL) levels were significantly higher in the azoospermia and severe oligospermia groups, while inhibin B (INHB) levels were significantly lower. Follicle-stimulating hormone (FSH) levels were elevated in all infertility groups. Differences in luteinizing hormone (LH) levels were observed between the azoospermia and oligospermia groups, and testosterone (T) levels were reduced in the azoospermia group. No significant differences in progesterone (PROG) and estradiol (E2) levels were observed between the groups (P>0.05). Conclusions: The evaluation of reproductive hormones,

Indexed as

Azoospermiaazoospermia factor microdeletion (AZF microdeletion)chromosome karyotypeoligospermiareproductive hormones

Identifiers

PMID42293857
PMCPMC13263875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.