Evidence map›Paper›PMID 42293839›Full record

ArticleTranslational andrology and urology2026

Tyrone L R Humphries, Xin Dong, Sharon J Del Vecchio, Aaron J Urquhart, Robert J Ellis, Hemamali Samaratunga, Julia Watson, Ross S Francis, Graham J Galloway, Glenda C Gobe and 2 more

Abstract read
In one paragraph

Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tyrone L R Humphries *Faculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0001-6735-6886
Xin Dong *Princess Alexandra Hospital, Woolloongabba, Australia.
Sharon J Del VecchioFaculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0002-2467-2106
Aaron J UrquhartFaculty of Medicine, The University of Queensland, Brisbane, Australia.
Robert J EllisFaculty of Medicine, The University of Queensland, Brisbane, Australia.ORCID https://orcid.org/0000-0001-5796-1791
Hemamali SamaratungaAquesta Uropathology, Toowong, Australia.
Julia WatsonPrincess Alexandra Hospital, Woolloongabba, Australia.
Ross S FrancisFaculty of Medicine, The University of Queensland, Brisbane, Australia.
Graham J GallowayTranslational Research Institute, Woolloongabba, Australia.ORCID https://orcid.org/0000-0002-0805-2775
Glenda C GobeFaculty of Medicine, The University of Queensland, Brisbane, Australia.
Simon T WoodPrincess Alexandra Hospital, Woolloongabba, Australia.
Carolyn E MountfordFaculty of Medicine, The University of Queensland, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current clinical management of clear cell renal cell carcinoma (ccRCC) frequently requires surgical excision. Surgery for suspected ccRCC is routinely carried out before histopathological diagnosis, yet up to 20% of enhancing small renal masses are benign and could be managed conservatively. Differences in tissue chemistry, using magnetic resonance spectroscopy of human renal neoplasia biopsies, showed a clear distinction between ccRCC, non-ccRCC and healthy kidney tissue. We aimed to develop a preoperative Methods: Using a 3T Prisma magnetic resonance imaging (MRI) scanner we developed an Results: Healthy kidneys were compared with three ccRCC lesions, each with a different grade and size. The chemical differences included increases in the resonance intensity for lipid methylene and methyl, choline and creatine. Conclusions: These MRI data now need to be substantiated with a larger study to characterize the malignant potential and relationship to grade and loss of cellular differentiation in ccRCC lesions

Indexed as

magnetic resonance spectroscopy (MRS)nuclear magnetic resonance (nuclear MR)Renal cell carcinoma (RCC)

Identifiers

PMID42293839
PMCPMC13263888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.