Evidence map›Paper›PMID 42293801›Full record

ArticlePlastic and reconstructive surgery. Global open2026

Dynamic Multiform Fat Grafting for Facial Rejuvenation.

Beibei Ren, Tongrong Guo

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Beibei RenFrom the Hangzhou United Bea Care Sixth Medical Cosmetology Hospital, Hangzhou City, Zhejiang Province, China.
Tongrong GuoFrom the Hangzhou United Bea Care Sixth Medical Cosmetology Hospital, Hangzhou City, Zhejiang Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Traditional fat grafting techniques predominantly rely on static assessment and homogeneous fat filling, yet clinical practice has revealed limitations such as poor adaptability to dynamic expressions and unnatural contour transitions. Recent studies have demonstrated that centrifugally stratified fat layers exhibit distinct biological properties. However, achieving harmonious integration of volumetric restoration and dynamic expression through precise dynamic evaluation combined with layered and progressive grafting of multimorphological fat remains a critical clinical challenge. Building on facial dynamized anatomy, this study proposes a dynamic assessment-multimorphological fat grafting strategy, aiming to establish a personalized rejuvenation protocol aligned with facial biomechanical principles. Methods: A total of 305 patients (19-56 y old) were enrolled from December 2019 to February 2023. Fat harvested from the thighs or abdomen was processed into 3 forms: high-density macrofat, high-density microfat, and stromal vascular fraction gel. These were injected dynamically into multiple facial regions, angles, depths, and layers using specialized cannulas. Follow-up ranged from 6 months to 3 years to assess clinical outcomes and patient satisfaction. Results: All 305 patients showed significant improvement in facial volume loss, skin elasticity, and fine wrinkles, achieving a rounded and youthful facial contour. Patient satisfaction rates were high, with 95.1% reporting satisfaction and 4.9% indicating basic satisfaction. No complications such as nodules or cysts were observed. Conclusions: Dynamic multiform fat grafting demonstrates high efficacy and patient satisfaction, offering natural and harmonious outcomes.

Identifiers

PMID42293801
PMCPMC13263092

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.