Evidence map›Paper›PMID 42293687›Full record

ArticleSynthetic and systems biotechnology2026

Engineering of fructose-6-phosphate aldolase for one-carbon conversion to mannitol in a designed biotransformation system.

Dandan Wang, Qianzhen Dong, Peng Chen, Yan Zeng, Yinlu Liu, Yuanxia Sun, Jianxin Tan, Jiangang Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dandan WangCollege of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Qianzhen DongTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Peng ChenTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Yan ZengTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Yinlu LiuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Yuanxia SunTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Jianxin TanCollege of Food Science and Technology, Hebei Agricultural University, Baoding, 071001, China.
Jiangang YangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing artificial synthetic pathways for converting one-carbon compounds into value-added chemicals represents a promising strategy for carbon-neutral manufacturing. Enzymatic C-C bond formation plays a central role in carbon-chain extension and structural diversification. Fructose-6-phosphate aldolase (FSA) has been employed in

Indexed as

Fructose-6-phosphate aldolaseMannitolMultienzyme systemOne-carbonReaction mechanism

Identifiers

PMID42293687
PMCPMC13259622

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.