Evidence map›Paper›PMID 42293588›Full record

SynthesisFrontiers in public health2026

Comparative efficacy of green exercise versus indoor exercise for depression and anxiety: a systematic review and network meta-analysis.

Yun Liang, Da-Yuan Wei, Su Min

Abstract readComparative StudySystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yun LiangDepartment of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Da-Yuan WeiDepartment of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Su MinDepartment of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Physical activity is a proven intervention for depression and anxiety, but the optimal environment for exercising remains debated. While "green exercise" (in nature) is theorized to offer superior mental health benefits to indoor exercise, a comprehensive quantitative ranking of these modalities against a no-exercise control is lacking. We aimed to determine the comparative efficacy of green exercise, indoor exercise, and control conditions for improving mental health outcomes. Methods: We conducted a systematic review and network meta-analysis of randomized controlled trials (RCTs). We searched PubMed, Embase, Web of Science, and CENTRAL from inception to December 2024 for RCTs comparing at least two of the following: green exercise, indoor exercise, or a no-exercise/standard care control group in adults. The primary outcome was a composite measure of mental health, including symptoms of depression, anxiety, and psychological distress. A random-effects network meta-analysis was performed to calculate standardized mean differences (SMDs) and rank the interventions using P-scores. The protocol was registered with PROSPERO (CRD420261279222). Results: Fifteen RCTs involving 809 participants were included. The network of evidence formed a closed three-node loop. Compared to control, green exercise showed a large and statistically significant effect on improving mental health (SMD = -0.96, 95% CI: -1.66 to -0.25). Indoor Exercise showed a small, non-significant beneficial trend (SMD = -0.21, 95% CI: -1.08 to 0.67). In direct comparison, green exercise was significantly superior to indoor exercise (SMD = -0.75, 95% CI: -1.32 to -0.18). Ranking analysis confirmed green exercise as the most effective intervention with near certainty ( Conclusion: Green exercise is a highly effective intervention for improving mental health, demonstrating benefits significantly greater than both indoor exercise and no-exercise control conditions. These findings strongly support the integration of nature-based physical activity into clinical practice and public health strategies for mental wellness. Systematic review registration: PROSPERO, CRD420261279222.

Indexed as

AnxietyDepressionExerciseExercise TherapyHumansRandomized Controlled Trials as Topicanxietydepressiongreen exerciseindoor exercisephysical activity

Identifiers

PMID42293588
PMCPMC13253268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.