Evidence map›Paper›PMID 42293522›Full record

ArticleFrontiers in microbiology2026

Development of a mixed microbial culture for robust high-throughput ex-situ thermophilic biomethanation.

Rajkumar Gangappa, Savvas Savvas, Sky Redhead, Tim Patterson, Sandra Esteves

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rajkumar GangappaWales Centre of Excellence for Anaerobic Digestion, Sustainable Environment Research Centre, Faculty of Computing, Engineering and Science, University of South Wales, Pontypridd, United Kingdom.
Savvas SavvasWales Centre of Excellence for Anaerobic Digestion, Sustainable Environment Research Centre, Faculty of Computing, Engineering and Science, University of South Wales, Pontypridd, United Kingdom.
Sky RedheadFaculty of Computing, Engineering and Science, University of South Wales, Pontypridd, United Kingdom.
Tim PattersonWales Centre of Excellence for Anaerobic Digestion, Sustainable Environment Research Centre, Faculty of Computing, Engineering and Science, University of South Wales, Pontypridd, United Kingdom.
Sandra EstevesWales Centre of Excellence for Anaerobic Digestion, Sustainable Environment Research Centre, Faculty of Computing, Engineering and Science, University of South Wales, Pontypridd, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ex-situ biomethanation using mixed microbial cultures is a promising approach for carbon capture and utilisation, converting CO₂ and renewable H₂ into grid-compatible methane. However, achieving high H₂/CO₂ throughputs at ambient pressure remains constrained by microbial competition and process instability. This study presents a novel operational strategy integrating autoclave pretreatment, targeted microbial conditioning, and intermittent washouts to achieve stable, high throughput ex-situ biomethanation using autoclaved, microbe rich sludge. Autoclave pretreatment of seed sludge reduced total bacteria by ~92.5%, while key methanogens,

Indexed as

ex-situ biomethanationmixed microbial culturepower to methanesustainable fuelthermophiles

Identifiers

PMID42293522
PMCPMC13256089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.