Evidence map›Paper›PMID 42293519›Full record

ArticleFrontiers in microbiology2026

The effect of elevated physiological temperatures on bacterial survival and antibiotic susceptibility in an

Robert Kamphof, Marielle Verheul, Rob G H H Nelissen, Mark G J de Boer, Bart G C W Pijls

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert KamphofDepartment of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands.
Marielle VerheulDepartment of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands.
Rob G H H NelissenDepartment of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands.
Mark G J de BoerDepartment of Clinical Epidemiology, Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, Leiden, Netherlands.
Bart G C W PijlsDepartment of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Prosthetic joint infection (PJI) is a devastating adverse outcome of total joint arthroplasty surgery, and is often accompanied by treatment failure. Due to a rise in the number of orthopaedic implants and global antimicrobial resistance, non-antibiotic strategies for preventing and treating orthopaedic infections are needed. This study investigates the effect of temperature in the physiological range on bacterial killing, bacterial adhesion and the antibiotic susceptibility of bacteria. Methods: Planktonic phase clinical isolates of methicillin-sensitive Results: Increasing the temperature from 32 to 42 °C reduced the minimum concentration required to kill Conclusion: These

Indexed as

arthroplastyheathyperthermiahypothermiaimplantsinfection preventionnormothermia

Identifiers

PMID42293519
PMCPMC13260641

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.