Evidence map›Paper›PMID 42293509›Full record

ArticleGeneral psychiatry2026

Depression meets obesity: Co-occurrence patterns, temporal trends and socioeconomic correlates across 199 countries and territories.

Yang Yang, Jingqi Kong, Jing Chen, Yihang Yang, Jingyao Liu, Runze Hu, Dexing Zhang, Zheng Liu

Abstract read
In one paragraph

Article in General psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yang YangDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0009-0006-8429-9573
Jingqi KongDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0009-0008-8764-1666
Jing ChenDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0000-0002-6640-7140
Yihang YangDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0009-0002-3926-8226
Jingyao LiuDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0009-0003-1032-9221
Runze HuDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0009-0003-2968-555X
Dexing ZhangSchool of Nursing The Hong Kong Polytechnic University Hong Kong China.ORCID https://orcid.org/0000-0003-0073-4752
Zheng LiuDepartment of Maternal and Child Health School of Public Health Peking University Beijing China.ORCID https://orcid.org/0000-0002-0405-2348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Depression and obesity are major global health burdens, yet the co-occurrence patterns and temporal trends of their comorbidity remain poorly characterised at the global level. Aims: To map the global patterns of co-occurring depression and obesity, quantify temporal trends of depression, obesity and comorbidity, forecast the prevalence of comorbidity up to 2035 and compare social indicators across groups stratified by their combined temporal trends of depression and obesity. Methods: Data were sourced from the Global Burden of Disease Study 2023, the NCD Risk Factor Collaboration and the World Bank Open Data repository. Countries and territories ( Results: For the four co-occurrence patterns, the consistently-low-prevalence group was primarily concentrated in Asia, the consistently-high-prevalence group in the Americas, the depression-dominant group in Africa and the obesity-dominant group in the Americas and Oceania. Concerning temporal trends, the prevalence of depression-obesity comorbidity increased globally (median AAPC: 4.66%; interquartile range [IQR]: 3.49%-6.30%). Notably, countries and territories in East Asia, Southeast Asia and sub-Saharan Africa had higher comorbidity AAPCs despite their low current prevalence. Temporal trends were categorised into four patterns: 44 (22.11%) countries and territories were classified into the double-fast-growing group (Southeast Asia, sub-Saharan Africa), 56 (28.14%) into the depression-driven-growing group (West Asia, North Africa, North America, Oceania), 56 (28.14%) into the obesity-driven-growing group (East Asia, Latin America and the Caribbean) and the remaining 43 (21.61%) into the double-slow-growing group (Europe, Australia and New Zealand). Predictive analysis indicated the median prevalence of depression-obesity comorbidity may increase to 833.32 (IQR: 532.07-1367.42) per 100 000 in 2030 and 869.35 (IQR: 544.11-1403.71) per 100 000 in 2035. Compared with the double-slow-growing group, the obesity-driven and double-fast-growing groups showed poorer socioeconomic status and healthcare resources; the depression-driven-growing group showed poorer healthcare resources. Conclusions: The prevalence of depression-obesity comorbidity increased globally. Particular attention is warranted for countries and territories with currently low comorbidity prevalence but rapidly increasing trends. Our findings also highlight the need for accessible interventions for countries and territories with poorer socioeconomic status and healthcare resources.

Indexed as

comorbiditydepressive disorderGlobal Burden of Diseaseobesity

Identifiers

PMID42293509
PMCPMC13261309

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.