Evidence map›Paper›PMID 42293501›Full record

ArticleRadiology case reports2026

From surgical debridement to laser-guided bone repair: An integrative approach to mandibular osteomyelitis.

Gustavo Q Câmara, Bianca Pulino, Bruno N Prado, Maitê Camargo, Geraldo Prestes de Camargo Filho, Raphael Capelli Guerra

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gustavo Q CâmaraHospital Sírio-Libanês, Instituto de Ensino e Pesquisa, São Paulo, São Paulo, Brazil.
Bianca PulinoHospital Sírio-Libanês, Instituto de Ensino e Pesquisa, São Paulo, São Paulo, Brazil.
Bruno N PradoHospital Sírio-Libanês, Instituto de Ensino e Pesquisa, São Paulo, São Paulo, Brazil.
Maitê CamargoCollege of Dentistry, Nova Southeastern University, Fort Lauderdale, Fl, USA.
Geraldo Prestes de Camargo FilhoCollege of Dentistry, Nova Southeastern University, Fort Lauderdale, Fl, USA.
Raphael Capelli GuerraHospital Sírio-Libanês, Instituto de Ensino e Pesquisa, São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic mandibular osteomyelitis is a challenging condition due to impaired vascularization, necrotic bone, and persistent infection, often requiring combined therapeutic approaches. We report the case of a 49-year-old male presenting with severe mandibular pain, purulent discharge, and radiographic evidence of bone sequestration and pathological fracture following tooth extraction. The patient was treated conservatively with surgical debridement associated with antimicrobial photodynamic therapy using 0.01% methylene blue activated by a 660 nm laser, followed by adjunctive low-level infrared laser therapy for photobiomodulation. Clinical and radiographic follow-up demonstrated resolution of infection, reduction of pain and inflammation, and progressive bone repair without adverse effects. This case highlights that the combination of photodynamic therapy and photobiomodulation may represent a safe and effective adjunctive approach in the management of chronic mandibular osteomyelitis, particularly in patients seeking less invasive alternatives to radical surgical procedures.

Indexed as

Low-intensity laser therapyMandibleMethylene blueOsteomyelitisPhotodynamic therapy

Identifiers

PMID42293501
PMCPMC13264344

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.