Evidence map›Paper›PMID 42293391›Full record

ArticleMaterials today. Bio2026

Dual-tunable liquid crystal-forming system enables sustained ropivacaine delivery for prolonged local analgesia.

Chuansheng Fu, Donghong Chen, Sihan Yu, Jiao Zhang, Qi Xie, Bingzheng Shen, Conglian Yang, Li Kong, Zhiping Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chuansheng FuTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Donghong ChenTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Sihan YuTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jiao ZhangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Qi XieTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Bingzheng ShenDepartment of Pharmacy, Renmin Hospital, Wuhan University, Wuhan, 430060, China.
Conglian YangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Li KongTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Zhiping ZhangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative pain management remains a challenge in clinical practice. Traditional local anesthetics often require repeated administration due to their short duration of action, which increases the risk of systemic toxicity and nerve damage. Herein, we developed an injectable, dual-tunable, low-ethanol lyotropic liquid crystal-forming system (LCFS) for sustained local ropivacaine (Rop) release, achieving long-lasting analgesia. Upon injection, the precursor solution transformed into a gel

Indexed as

In situ gelationLiquid crystal-forming systemLong-acting local analgesiaRopivacaineSustained-release

Identifiers

PMID42293391
PMCPMC13264336

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.