ArticleFrontiers in reproductive health2026
Adverse pregnancy outcomes and risk factors in women with primary Sjögren's syndrome: data from a prospective study.
Article in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to describe the pregnancy outcomes in patients with primary Sjögren's syndrome (SjD) and identify risk factors for adverse pregnancy outcomes (APO) in a prospective single center study. Methods: We described the outcomes of 114 pregnant women who fulfilled the established criteria for SjD and analyzed the risk factors for adverse outcomes using multiple factors logistic regression. Results: The fetal and maternal outcomes in 114 pregnancies were as follows:100 (87.7%) live births, 11(9.6%) miscarriages (first-trimester pregnancy loss), three (2.6%) stillbirths, six (5.3%) cases with intrauterine growth restriction, five (4.1%) preterm deliveries, seven (6.1%) cases with small-for-gestational-age birth weight, and five (4.4%) cases with preeclampsia or eclampsia. Multivariate analysis revealed that age at pregnancy (odds ratio [OR]:1.402, Conclusion: In our cohort, women with subchorionic hemorrhage or anti-U1RNP antibody positivity require close monitoring because these factors are associated with a higher risk of APO.
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