ArticleFrontiers in nutrition2026
Comparison of the predictive value of CONUT, NLR, and PNI for 6-month and 1-year mortality in middle-aged and older adults with hip fractures: a retrospective study.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to compare the predictive value of three preoperative nutritional status scores-Controlling Nutritional Status (CONUT) score, Neutrophil-to-Lymphocyte Ratio (NLR), and Prognostic Nutritional Index (PNI)-for 6-month and 12-month mortality in middle-aged and older adults with hip fractures. Methods: A retrospective cohort study was conducted on 198 middle-aged and older adults (≥50 years) who underwent surgical treatment for hip fractures at Jinjiang Municipal Hospital (Shanghai Sixth People's Hospital Fujian) between January 2020 and December 2021. Preoperative laboratory data were used to calculate CONUT, NLR, and PNI scores. Receiver operating characteristic (ROC) curves were used to evaluate predictive efficacy, and Kaplan-Meier analysis was used to compare mortality across nutritional status subgroups. Results: Thirty patients (15.15%) died within 6 months and 40 (20.20%) within 12 months. Multivariate analysis suggested high CONUT score was independently associated with short-term mortality. The CONUT score significantly predicted 6-month (AUC = 0.620, 95% CI: 0.531-0.710, Conclusion: Among the three scores, the CONUT score was associated with better predictive performance for 6-month and 12-month mortality in middle-aged and older adults with hip fractures. Preoperative CONUT score assessment may help identify high-risk patients and support targeted nutritional interventions. NLR and PNI showed limited value in predicting short-term mortality in this population. Trial registration: This study has been registered in national medical research registration and filing information system of China, www.medicalresearch.org.cn, Trail registration number: MR-35-24-034127. Registration date: 28 August 2024.
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