Evidence map›Paper›PMID 42293186›Full record

Trial reportFrontiers in nutrition2026

Efficacy of

Ke Chen, Shanshan Jin, Yang Nie, Nianyang He, Haixia Chen, Jie Yuan, Xiaohui Li, Min-Tze Liong

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ke ChenDepartment of Clinical Nutrition, Chengdu Women's & Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Shanshan JinDepartment of Clinical Nutrition, Chengdu Women's & Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Yang NieDepartment of Child Health Care, Chongzhou Maternal and Child Health Care Hospital, Chongzhou, Sichuan, China.
Nianyang HeDepartment of Child Health Care, Xindu Maternal and Child Health Care Hospital, Chengdu, Sichuan, China.
Haixia ChenBaoxing Central for Disease Prevention and Control, Yaan, Sichuan, China.
Jie YuanLaboratory of Microbiology, Immunology, and Metabolism, DiPROBIO (Shanghai) Co., Ltd., Shanghai, China.
Xiaohui LiLaboratory of Microbiology, Immunology, and Metabolism, DiPROBIO (Shanghai) Co., Ltd., Shanghai, China.
Min-Tze LiongLaboratory of Microbiology, Immunology, and Metabolism, DiPROBIO (Shanghai) Co., Ltd., Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early childhood is a critical period for immune development, with eczema and respiratory infections representing common health challenges. This study investigated the efficacy of Methods: In a randomized, double-blind, placebo-controlled trial, 360 formula-fed infants and children aged below 3 years old with elevated allergy risk received daily Results: The probiotic group demonstrated significantly reduced eczema incidence (27.6% vs. 69.5%, RR: 0.398, Conclusions: Clinical Trial Registration: ChiCTR2300074956.

Indexed as

Bifidobacterium animalis subsp. lactis BLa80childgut microbiotaprobioticrandomized controlled trial

Identifiers

PMID42293186
PMCPMC13255822

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.